Background: The grading of intracochlear endolymphatic hydrops (EH) in Meniere's disease (MD) varies and lacks uniformity.
Aims: To compare the grading consistency and correlation between different grade methods of intracochlear EH and hearing loss.
Materials And Methods: Thirty-one patients diagnosed with MD underwent gadolinium-enhanced magnetic resonance imaging. Two radiologists graded the cochlea EH according to M1, M2, M3, or M4. We analysed the grading consistency and correlation between the EH degrees and hearing loss.
Results: The weighted kappa coefficients for inter-observer and intra-observer agreements for grading using M1 were good, whereas those for M2, M3, and M4 are excellent (all < 0.001). The cochlear EH degree based on M2 was correlated with the low-to-mid frequencies, high frequencies, full frequencies, and MD clinical stage (all < 0.05). The degrees based on M1, M3, M4 were only relevant to some of the 4 items.
Conclusions: The grading consistency of M2, M3, M4 is relatively higher than that of M1, and M2 shows the strongest correlation with hearing loss.
Significance: Our results provide a more accurate method for assessing the clinical severity of MD.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1080/00016489.2023.2209134 | DOI Listing |
Laryngoscope
January 2025
Department of Otology and Skull Base Surgery, Eye, Ear, Nose, and Throat Hospital, Fudan University, Shanghai, China.
Objective: Endolymphatic sac tumors (ELSTs), as rare low-grade neoplasms, are primarily treated with surgery. This study analyzes the characteristics of tumor-infiltrating leukocytes (TILs) in ELSTs and their relationships with clinical features to explore the potential for immunotherapy in ELSTs.
Methods: Clinical data and tumor specimens of 10 ELSTs patients who underwent surgery were retrieved.
FASEB J
January 2025
Department of Otolaryngology-Head and Neck Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Meniere's disease (MD) is an inner ear disease characterized by endolymphatic hydrops (EH). Maintaining a regular daily routine is crucial for MD patients. However, the relationship between circadian rhythms and MD remains unclear.
View Article and Find Full Text PDFJ Clin Med
December 2024
Département d'ORL, Centre Hospitalier Universitaire de Saint Etienne, 42055 Saint-Etienne, France.
: Spontaneous nystagmus during vertigo attacks of Menière's disease has been essentially described as horizontal, beating ipsilaterally (irritative type) or contralaterally (deficit type) to the hearing loss. Our main objective was to describe the characteristics of nystagmus during vertigo attacks. The second objective was to determine the feasibility of self-video recording of eye movements by a mobile phone.
View Article and Find Full Text PDFJ Formos Med Assoc
January 2025
Department of Otolaryngology, National Taiwan University Hospital, Taipei, Taiwan; Department of Otolaryngology, Far Eastern Memorial Hospital, New Taipei, Taiwan. Electronic address:
Front Neurol
December 2024
Department of Otorhinolaryngology-Head and Neck Surgery, Tongji Medical College, Union Hospital, Huazhong University of Science and Technology, Wuhan, China.
Background: The pathological hallmark of Ménière's disease is endolymphatic hydrops, which can lead to an increase in basilar membrane stiffness and, consequently, an acceleration of the traveling wave of sound. The cochlear hydrops analysis masking procedure (CHAMP), which is an auditory brainstem response test masked at various frequencies with high-pass noise masking, uses the principle of the traveling wave velocity theory to determine the presence of endolymphatic hydrops.
Purpose: This study aimed to review the previous results of the CHAMP, expound the principles and key indicators, and discuss its clinical significance in diagnosing Ménière's disease.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!