Here, we report the synthesis and evaluation of fullerene C60 nanoparticles' (FC60 NPs) therapeutic efficacy in animals with aluminum-induced oxidative stress. Effects of FC60 NPs on the altered activity levels of neurobiochemical enzymes and oxidative parameters in brain and liver tissues have been evaluated. Aluminum was injected for 3 weeks and from the beginning of the third week, FC60 NPs were injected for 1 week. Administration of FC60 NPs showed a significant improvement in the altered activity level of the selected markers. Results suggest synthesized FC60 NPs as a therapeutic option for the treatment of neurodegenerative diseases.
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| http://dx.doi.org/10.2217/nnm-2023-0007 | DOI Listing |
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