What Is Already Known About This Topic?: The largest and longest outbreak of diarrhea, which was complicated with hemolytic uremic syndrome (HUS) caused by enterohemorrhagic (EHEC) O157:H7, occurred in Xuzhou City and its adjacent areas from 1999 to 2000 in China.
What Is Added By This Report?: According to surveillance results from 2001 to 2021, there was a significant decrease in the isolation rate of O157:H7, and cattle and sheep remained the primary hosts. However, non-Shiga toxin-producing O157:H7 emerged as the dominant strain, with +- strains following closely behind.
What Are The Implications For Public Health Practice?: National surveillance of O157:H7 effectively serves as an early warning system and guidance for assessing the intensity and trend of disease epidemics. It is crucial to raise awareness of the public health risks associated with Shiga toxin-producing .
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http://dx.doi.org/10.46234/ccdcw2023.057 | DOI Listing |
Front Psychiatry
December 2024
Department of Community and Health Education, School of Public Health, Xuzhou Medical University, Xuzhou, China.
Background: Pregnancy, a transformative phase, is often fraught with considerable psychological stress. Within the context of Chinese culture, characterized by intricate family dynamics, societal expectations, and deeply rooted traditional beliefs, the manifestation of stress during pregnancy may present with distinct nuances. The adaptation and validation of the Perceived Stress Scale (PSS-10) for the Chinese context are pivotal for a nuanced understanding and effective intervention for the stressors encountered by pregnant women in China.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Respiratory and Critical Care Medicine, The Second People's Hospital of Fuyang City, Fuyang, Anhui, People's Republic of China.
Background: Life expectancy at age 70 has continued to rise globally over the past 30 years. However, a comprehensive assessment of the burden of COPD in older adults is lacking. We aimed to estimate the burden of COPD and its attributable risk factors among adults aged ≥70 years.
View Article and Find Full Text PDFJ Immunother Cancer
January 2025
Cancer Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China
Background: Siglec-E is an immune checkpoint inhibitory molecule. Expression of Siglec-E on the immune cells has been shown to promote tumor regression. This study aimed to develop an adenovirus (Ad) vaccine targeting Siglec-E and carbonic anhydrase IX (CAIX) (Ad-Siglec-E/CAIX) and to evaluate its potential antitumor effects in several preclinical renal cancer models.
View Article and Find Full Text PDFHepatobiliary Pancreat Dis Int
December 2024
Department of Clinical Laboratory, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou 215008, China. Electronic address:
Background: Despite the insights into the role of aldehyde dehydrogenase 1 family member A1 (ALDH1A1) in various liver diseases, the expression and its prognostic significance in patients with hepatitis E virus-related acute liver failure (HEV-ALF) remain unclear. This study delved into the assessment of serum exosome-derived ALDH1A1 expression and its prognostic implications for HEV-ALF patients.
Methods: Between January 2018 and December 2023, a total of 226 individuals with acute hepatitis E (AHE) and 210 patients with HEV-ALF were recruited from member units of Chinese Consortium for the Study of Hepatitis E.
Front Endocrinol (Lausanne)
January 2025
Department of Endocrinology, Huai'an Hospital Affiliated to Xuzhou Medical University and Huai'an Second People's Hospital, Huai'an, Jiangsu, China.
Objectives: To examine the association between the age at onset of diabetes and the risk of all-cause mortality in a population of individuals diagnosed with type 2 diabetes mellitus (T2DM) and to identify risk factors associated with all-cause mortality in young-onset T2DM (YOD) patients in China.
Methods: This study utilized a cohort of 9759 patients who were diagnosed with T2DM and who were registered and enrolled in the National Basic Public Health Service Management Program in Qinghe District (now Qingjiangpu District) and Huai'an District, Huai'an City, Jiangsu Province, China. The patients were observed from November 2013 to July 2014, and all-cause mortality data were obtained by comprehensive matching with the Huai'an City Resident Mortality Database as of December 31, 2019.
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