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Photobiomodulation in carpal tunnel syndrome with pain, strength, and functionality analysis: a systematic review and meta-analysis.
Lasers Med Sci
January 2025
Universidade Estadual do Oeste do Paraná - Unioeste, Campus Cascavel, Universitaria St. 2069, CascavelParaná, 85819-110, Brazil.
Article Synopsis
- Carpal tunnel syndrome (CTS) is a condition caused by pressure on the median nerve, and treatments like low-intensity laser therapy (LLLT) are being researched for their effectiveness in relief.
- A systematic review was conducted using multiple databases to analyze the impact of LLLT on symptoms like pain, strength, and hand functionality among 13 selected randomized controlled trials.
- Results showed that LLLT did not significantly improve pain or handgrip strength, although it had some potential benefits for hand functionality.
Catalogue of inherited autosomal recessive disorders found amongst the Roma population of Europe.
Eur J Med Genet
December 2024
Department of Clinical Genetics, Our Lady's Children's Hospital, Children's' Health Ireland, Dublin, Ireland; Academic Centre on Rare Diseases, University College Dublin, Dublin, Ireland; National Centre for Inherited Metabolic Disorders, Children's Health Ireland, Temple Street Dublin, Ireland. Electronic address:
Background: The Roma population are an endogamous, genetically isolated, minority population who migrated from North-Western India to Europe from the 10th Century throughout the Byzantine period and continues to the present day. Approximately 10-12 million Romani people reside in segregated settlements in Europe, and smaller populations live in North America and China. In addition to the endogamy, they also practice consanguinity.
View Article and Find Full Text PDFRecent trends and biases in mesophotic ecosystem research.
Biol Lett
December 2024
California Academy of Sciences, San Francisco, CA, USA.
Article Synopsis
- Mesophotic ecosystems, found between 30-150 meters deep, cover a large part of the oceans but have been under-researched due to accessibility challenges.
- Recent advances in underwater technology and increased interest have led to significant exploration of these ecosystems, particularly tropical and temperate coral reefs.
- An updated database review identified four main research biases: uneven geographical studies, differences in depth focus, varied research fields, and a scarcity of long-term studies, indicating areas for improvement in future research.
Genetics of female and male reproductive traits and their relationship with health, longevity and consequences for offspring.
Nat Aging
December 2024
Leverhulme Centre for Demographic Science, Nuffield Department of Population Health, University of Oxford and Nuffield College, Oxford, UK.
Substantial shifts in reproductive behaviors have recently taken place in many high-income countries including earlier age at menarche, advanced age at childbearing, rising childlessness and a lower number of children. As reproduction shifts to later ages, genetic factors may become increasingly important. Although monogenic genetic effects are known, the genetics underlying human reproductive traits are complex, with both causal effects and statistical bias often confounded by socioeconomic factors.
View Article and Find Full Text PDFSex is an important covariate in all genetic and epigenetic research due to its role in the incidence, progression and outcome of many phenotypic characteristics and human diseases. Amyotrophic lateral sclerosis (ALS) is a motor neuron disease with a sex bias towards higher incidence in males. Here, we report for the first time a blood-based epigenome-wide association study meta-analysis in 9274 individuals after stringent quality control (5529 males and 3975 females).
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