Objective: To investigate the changes in spinal-pelvic sagittal parameters from preoperative standing to prone position in old traumatic spinal fractures with kyphosis.
Methods: The clinical data of 36 patients admitted between December 2016 and June 2021 for surgical treatment of old traumatic spinal fractures with kyphosis, including 7 males and 29 females, aged from 50 to 79 years (mean, 63.9 years), were retrospectively analyzed. Lesion segments included 2 cases of T , 12 cases of T , 2 cases of T , 4 cases of T and L , 12 cases of L , 2 cases of L , 1 case of L , and 1 case of L . The disease duration ranged from 4 to 120 months, with an average of 19.6 months. Surgical procedures included Smith-Petersen osteotomy in 4 cases, Ponte osteotomy in 6 cases, pedicle subtraction osteotomy in 2 cases, and improved fourth level osteotomy in 18 cases; the remaining 6 cases were not osteotomized. The bone mineral density ranged from -3.0 to 0.5 T, with a mean of -1.62 T. The spinal-pelvic sagittal parameters from preoperative standing to prone positions were measured, including local kyphosis Cobb angle (LKCA), thoracic kyphosis (TK), lumbar lordosis (LL), sacral slope (SS), pelvic tilt (PT), and PI and LL mismatch (PI-LL). The kyphotic flexibility=(preoperative standing LKCA-preoperative prone LKCA)/preoperative standing LKCA×100%. Spinal-pelvic sagittal parameters were compared between standing position and prone position before operation, and Pearson correlation was used to judge the correlation between the parameters of standing position and prone position before operation.
Results: When the position changed from standing to prone, LKCA and TK decreased significantly ( <0.05), while SS, LL, PT, and PI-LL had no significant difference ( >0.05). Pearson correlation analysis showed that LL was significantly correlated with SS and PI-LL in both standing and prone positions ( <0.05), and the correlation strength between LL and SS in prone position was higher than that in standing position. In the standing position, LKCA was significantly correlated with SS and PT ( <0.05). However, when the position changed from standing to prone, the correlation between LKCA and SS and PT disappeared, while PT and PI-LL was positive correlation ( <0.05). The kyphotic flexibility was 25.13%-78.79%, with an average of 33.85%.
Conclusion: For the patients of old traumatic spinal fractures with kyphosis, the preoperative LKCA and TK decrease significantly from standing position to prone position, and the correlation between spinal and pelvic parameters also changed, which should be taken into account in the formulation of preoperative surgical plan.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196967 | PMC |
http://dx.doi.org/10.7507/1002-1892.202301070 | DOI Listing |
J Am Mosq Control Assoc
January 2025
Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA, 30602.
Accurate enumeration of mosquito eggs is crucial for various entomologic studies, including investigations into mosquito fecundity, life history traits, and vector control strategies. Traditional manual counting methods are labor intensive and prone to human error, highlighting the need for automated systems. This study presents a stand-alone automated mosquito egg counting system using a Raspberry Pi computer, high-quality camera, light-emitting diode ring light source, and a Python script leveraging the Open Source Computer Vision library.
View Article and Find Full Text PDFProtein Sci
February 2025
Department of Biotechnology and Bioengineering, Sandia National Laboratories, Livermore, California, USA.
Engineered monoclonal antibodies have proven to be highly effective therapeutics in recent viral outbreaks. However, despite technical advancements, an ability to rapidly adapt or increase antibody affinity and by extension, therapeutic efficacy, has yet to be fully realized. We endeavored to stand-up such a pipeline using molecular modeling combined with experimental library screening to increase the affinity of F5, a monoclonal antibody with potent neutralizing activity against Venezuelan Equine Encephalitis Virus (VEEV), to recombinant VEEV (IAB) E1E2 antigen.
View Article and Find Full Text PDFSci Rep
January 2025
College of Forestry, Shenyang Agricultural University, Shenyang, 110866, China.
Poplar (Populus simoni) plantations are crucial in the sandy regions of western Liaoning, serving key roles in wind protection, sand stabilization, soil moisture regulation, and carbon sequestration. However, challenges such as suboptimal stand quality and limited ecological benefits persist. This study aims to elucidate the growth dynamics of poplar plantations and their impact on soil moisture content and soil carbon content in this region.
View Article and Find Full Text PDFNeural Netw
January 2025
College of Intelligence and Computing, Tianjin University, Tianjin, 300350, China. Electronic address:
Federated Learning (FL) is a popular framework for data privacy protection in distributed machine learning. However, current FL faces some several problems and challenges, including the limited amount of client data and data heterogeneity. These lead to models trained on clients prone to drifting and overfitting, such that we just obtain suboptimal performance of the aggregated model.
View Article and Find Full Text PDFAcc Chem Res
January 2025
Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Innovative Drug Research Center, School of Pharmaceutical Sciences, Chongqing University, Chongqing 401331, China.
ConspectusThe Mannich reaction, involving the nucleophilic addition of an enol(ate) intermediate to an imine or iminium ion, is one of the most widely used synthetic methods for the synthesis of β-amino carbonyl compounds. Nevertheless, the homo-Mannich reaction, which utilizes a homoenolate intermediate as the nucleophilic partner and provides straightforward access to the valuable γ-amino carbonyl compounds, remains underexplored. This can be largely attributed to the difficulties in generation and manipulation of the homoenolate species, despite various homoenolate equivalents that have been developed.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!