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Final clinical diagnosis in cases of histopathologic psoriasiform dermatitis: retrospective cross-sectional analysis of a Southeastern United States population, 2004-2017.
Arch Dermatol Res
January 2025
Department of Dermatology, Duke University Medical Center, Durham, NC, USA.
Background: Psoriasiform dermatitis can be defined both clinically and histologically, but is not a traditionally recognized clinical or histologic diagnosis.
Objective: Analyze the final clinical diagnosis, demographics and clinical characteristics in patients with histologic psoriasiform dermatitis.
Methods: Retrospective cross-sectional analysis of patients with histologic psoriasiform dermatitis 2004-2017.
Socioeconomic inequality in the outcomes of a psychological intervention for depression for South Africans with a co-occurring chronic disease: A decomposition analysis.
Soc Sci Med
December 2024
Curtin enAble Institute, Faculty of Health Sciences, Curtin University, Perth, WA, Australia; Mental Health, Alcohol, Substance Use and Tobacco Research Unit, South African Medical Research Council, Francie van Zyl Drive, Tygerberg, Cape Town, South Africa; Division of Addiction Psychiatry, Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa. Electronic address:
Task-shared psychological interventions are effective for reducing the severity of depression symptoms, but differences in treatment outcome by socioeconomic status is uncertain. This study examines socioeconomic inequalities (SEI) in depression outcomes among people with HIV and/or diabetes who participated in a cluster randomised controlled trial in the Western Cape Province of South Africa. The trial took place at 24 primary care clinics randomised to deliver a task-shared psychological intervention or treatment as usual (TAU).
View Article and Find Full Text PDFEvolution and ecology of anti-defence systems in phages and plasmids.
Curr Biol
January 2025
Laboratory of Biochemistry, Wageningen University, 6708 WE Wageningen, The Netherlands. Electronic address:
Prokaryotes (Bacteria and Archaea) encode a highly diversified arsenal of defence systems that protect them against mobile genetic elements, such as phages and plasmids. In turn, mobile genetic elements encode anti-defence systems that allow them to escape the activity of these defence systems. This has resulted in an evolutionary arms race in which defence systems and anti-defence systems evolve and adapt continuously, driving intriguing innovation and enormous diversification on both sides.
View Article and Find Full Text PDFIron nutrition and COVID-19 among Nigerian healthcare workers.
Evol Med Public Health
December 2024
Department of Anthropology, Michigan State University, East Lansing, MI, USA.
Background And Objectives: The optimal iron hypothesis (OIH) posits that risk for infection is lowest at a mild level of iron deficiency. The extent to which this protection results from arms race dynamics in the evolution of iron acquisition and sequestration mechanisms is unclear. We evaluated the OIH with regard to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), an emerging infectious agent.
View Article and Find Full Text PDFExtravillous trophoblasts reverse the decidualization induced increase in matrix production by secreting TGFβ antagonists Emilin-1 and Gremlin-1.
Cells Dev
January 2025
Department of Biomedical Engineering, University of Connecticut, Storrs, CT, United States of America; Department of Biomedical Engineering, University of Connecticut Health, Farmington, CT, United States of America; Jackson Laboratory, Farmington, CT, United States of America. Electronic address:
The maternal-fetal interface has long been considered as a frontier for an evolutionary arms race due to the close juxtaposition of genetically distinct tissues. In hemochorial species with deep placental invasion, including in humans, maternal stroma prepares its defenses against deep trophoblast invasion by decidualization, a differentiation process characterized by increased stromal cell matrix production, and contractile force generation. Decidualization has evolved from an ancestral wound healing response of fibroblast activation by the endometrial stroma.
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