The electrochemical performance of NiCoO with urea precursors was evaluated in order to develop a non-enzymatic urea sensor. In this study, NiCoO nanostructures were synthesized hydrothermally at different concentrations of urea and characterized using scanning electron microscopy and X-ray diffraction. Nanostructures of NiCoO exhibit a nanorod-like morphology and a cubic phase crystal structure. Urea can be detected with high sensitivity through NiCoO nanostructures driven by urea precursors under alkaline conditions. A low limit of detection of 0.05 and an analytical range of 0.1 mM to 10 mM urea are provided. The concentration of 006 mM was determined by cyclic voltammetry. Chronoamperometry was used to determine the linear range in the range of 0.1 mM to 8 mM. Several analytical parameters were assessed, including selectivity, stability, and repeatability. NiCoO nanostructures can also be used to detect urea in various biological samples in a practical manner.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135918PMC
http://dx.doi.org/10.3390/bios13040444DOI Listing

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