AI Article Synopsis
- Scientists have learned a lot about tiny things in our bodies, like molecules and cells, over the past 100 years.
- * New tools, like a special AI called AlphaFold2, help us understand the shapes and jobs of proteins better than ever before.
- * With all this new knowledge, researchers hope to find new medicines to help people feel better.
Article Abstract
The past century has witnessed an exponential increase in our atomic-level understanding of molecular and cellular mechanisms from a structural perspective, with multiple landmark achievements contributing to the field. This, coupled with recent and continuing breakthroughs in artificial intelligence methods such as AlphaFold2, and enhanced computational power, is enabling our understanding of protein structure and function at unprecedented levels of accuracy and predictivity. Here, we describe some of the major recent advances across these fields, and describe, as these technologies coalesce, the potential to utilise our enhanced knowledge of intricate cellular and molecular systems to discover novel therapeutics to alleviate human suffering.
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| http://dx.doi.org/10.1016/j.sbi.2023.102601 | DOI Listing |
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