Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167377PMC
http://dx.doi.org/10.3389/fncel.2023.1191743DOI Listing

Publication Analysis

Top Keywords

editorial glial
4
glial cells
4
cells emerging
4
emerging therapeutic
4
therapeutic target
4
target pathobiology
4
pathobiology central
4
central nervous
4
nervous system
4
system disorders
4

Similar Publications

Introduction: Remyelination of demyelinated axons can occur as an endogenous repair mechanism in multiple sclerosis (MS), but its efficacy varies between both MS individuals and lesions. The molecular and cellular mechanisms that drive remyelination remain poorly understood. Here, we studied the relation between microglia activation and remyelination activity in MS.

View Article and Find Full Text PDF

Bioaugmented design and functional evaluation of low damage implantable array electrodes.

Bioact Mater

May 2025

State Key Laboratory for Manufacturing System Engineering, School of Mechanical Engineering, Xi'an Jiaotong University, China.

Implantable neural electrodes are key components of brain-computer interfaces (BCI), but the mismatch in mechanical and biological properties between electrode materials and brain tissue can lead to foreign body reactions and glial scarring, and subsequently compromise the long-term stability of electrical signal transmission. In this study, we proposed a new concept for the design and bioaugmentation of implantable electrodes (bio-array electrodes) featuring a heterogeneous gradient structure. Different composite polyaniline-gelatin-alginate based conductive hydrogel formulations were developed for electrode surface coating.

View Article and Find Full Text PDF

Special Issue: Recent Advances in Microglia Research.

Int J Mol Sci

January 2025

Department of Health Sciences, Section of Clinical Pharmacology and Oncology, University of Florence, Viale Pieraccini 6, 50139 Firenze, Italy.

This Editorial introduces the new Special Issue, published in the and entitled "Recent Advances in Microglia Research", which covers this important topic with a collection of five valuable contributions: three Original Research Articles and two Reviews [...

View Article and Find Full Text PDF

Plasma levels of glial fibrillary acidic protein and neurofilament light chain in patients with chronic migraine: a multicenter case-control study.

Neurol Sci

January 2025

Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Via Mosè Bianchi 90, 20149, Milan, Italy.

Objective: Plasma glial fibrillary acidic protein (pGFAP) and plasma neurofilament light chain (pNfL) levels reflect astrocyte activation and neuronal damage, respectively. Whether these phenomena play a role in migraine is unknown. This study aimed to compare pGFAP and pNfL levels in patients with chronic migraine (CM) and age-matched controls and to analyze their relation with clinical features.

View Article and Find Full Text PDF

The growing global prevalence of diabetes mellitus (DM), along with its associated complications, continues to rise. When clinically detected most DM complications are irreversible. It is therefore crucial to detect and address these complications early and systematically in order to improve patient care and outcomes.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!