AI Article Synopsis

  • * After stopping Qing-Dai, her PAH symptoms improved quickly, and her REVEAL 2.0 risk score for PAH severity dropped from high risk to low risk in just 10 days.
  • * The case highlights that discontinuing Qing-Dai can lead to rapid recovery from its adverse effects, and REVEAL 2.0 is valuable for assessing PAH risk in patients on this medication.

Article Abstract

Unlabelled: A 20-year-old woman using Qing-Dai for about 7 years for intractable ulcerative colitis was admitted to the emergency room because of dyspnea and syncope following exertion. The patient was diagnosed with drug-induced pulmonary arterial hypertension (PAH). Discontinuation of Qing-Dai rapidly improved PAH symptoms. The REVEAL 2.0 risk score, which is useful for assessing the severity of PAH and predicting prognosis, improved from high risk (12) to low risk (4) within 10 days. Discontinuing long-term use of Qing-Dai can rapidly improve Qing-Dai-induced PAH.

Learning Objective: Discontinuing the long-term use of Qing-Dai used for treating ulcerative colitis (UC) can rapidly improve Qing-Dai induced pulmonary arterial hypertension (PAH). REVEAL 2.0 risk score in patients who developed PAH due to Qing-Dai was useful for screening PAH in patients taking Qing-Dai for treatment of UC.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173393PMC
http://dx.doi.org/10.1016/j.jccase.2023.02.003DOI Listing

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