Recently, pre-trained deep learning (DL) models have been employed to tackle and enhance the performance on many tasks such as skin cancer detection instead of training models from scratch. However, the existing systems are unable to attain substantial levels of accuracy. Therefore, we propose, in this paper, a robust skin cancer detection framework for to improve the accuracy by extracting and learning relevant image representations using a MobileNetV3 architecture. Thereafter, the extracted features are used as input to a modified Hunger Games Search (HGS) based on Particle Swarm Optimization (PSO) and Dynamic-Opposite Learning (DOLHGS). This modification is used as a novel feature selection to alloacte the most relevant feature to maximize the model's performance. For evaluation of the efficiency of the developed DOLHGS, the ISIC-2016 dataset and the PH2 dataset were employed, including two and three categories, respectively. The proposed model has accuracy 88.19% on the ISIC-2016 dataset and 96.43% on PH2. Based on the experimental results, the proposed approach showed more accurate and efficient performance in skin cancer detection than other well-known and popular algorithms in terms of classification accuracy and optimized features.
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http://dx.doi.org/10.3390/diagnostics13091579 | DOI Listing |
Front Med (Lausanne)
December 2024
Department of Oncology, Ganzhou People's Hospital, Ganzhou, China.
Background: Immune checkpoint inhibitors (ICIs) have been widely applicated for the treatment of patients with advanced esophageal cancer. Skin-related adverse reactions are frequent with ICIs, with toxic epidermal necrolysis (TEN) being a severe and potentially life-threatening cutaneous reaction.
Case Presentation: We present a case of a 70-year-old male with locally advanced esophageal cancer who developed severe toxic epidermal necrolysis (TEN) after 18 days of tislelizumab combined with chemotherapy.
Background: Melanoma is the fourth leading cause of cancer-related death worldwide. The continuous exploration and reporting of risk factors of melanoma is important for standardizing and reducing the incidence of the disease. Calcium signaling is a promising therapeutic target for melanoma; however, the relationship between total serum calcium levels and melanoma development remains unclear.
View Article and Find Full Text PDFEXCLI J
November 2024
Department of Diagnostics and Cancer Immunology, Greater Poland Cancer Center, 15 Garbary Street, 61-866 Poznan, Poland.
Cutaneous melanoma is the deadliest form of skin cancer. Despite advancements in treatment, many patients still face poor outcomes. A deeper understanding of the mechanisms involved in melanoma pathogenesis is crucial for improving diagnosis and therapy.
View Article and Find Full Text PDFClin Hematol Int
January 2025
Service d'Hématologie Clinique et Thérapie Cellulaire Hôpital Saint-Antoine.
Individuals with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) have a high risk of developing other malignancies (OMs). The development of OMs may be associated with the advanced age of CLL/SLL patients, presence of a tumor-promoting microenvironment, immune alterations inherent to CLL/SLL, or chemotherapy. Importantly, the occurrence of OMs following frontline fludarabine, cyclophosphamide and rituximab (FCR) treatment is associated with a reduction in the overall survival (OS).
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