AI Article Synopsis
- This study assesses the effectiveness of dual-source dual-energy CT (DECT) in creating virtual non-contrast images compared to traditional non-contrast scans, particularly in obese patients.
- A total of 253 oncologic patients were examined through both DECT and single-energy CT (SECT), with a focus on radiation dose and image quality across different BMI categories.
- Results showed that DECT achieved a significant reduction in radiation exposure compared to SECT but faced challenges with incomplete liver imaging coverage in obese patients.
Article Abstract
Objectives: Dual-source dual-energy CT (DECT) facilitates reconstruction of virtual non-contrast images from contrast-enhanced scans within a limited field of view. This study evaluates the replacement of true non-contrast acquisition with virtual non-contrast reconstructions and investigates the limitations of dual-source DECT in obese patients.
Materials And Methods: A total of 253 oncologic patients (153 women; age 64.5 ± 16.2 years; BMI 26.6 ± 5.1 kg/m) received both multi-phase single-energy CT (SECT) and DECT in sequential staging examinations with a third-generation dual-source scanner. Patients were allocated to one of three BMI clusters: non-obese: <25 kg/m ( = 110), pre-obese: 25-29.9 kg/m ( = 73), and obese: >30 kg/m ( = 70). Radiation dose and image quality were compared for each scan. DECT examinations were evaluated regarding liver coverage within the dual-energy field of view.
Results: While arterial contrast phases in DECT were associated with a higher CTDI than in SECT (11.1 vs. 8.1 mGy; < 0.001), replacement of true with virtual non-contrast imaging resulted in a considerably lower overall dose-length product (312.6 vs. 475.3 mGy·cm; < 0.001). The proportion of DLP variance predictable from patient BMI was substantial in DECT (R = 0.738) and SECT (R = 0.620); however, DLP of SECT showed a stronger increase in obese patients ( < 0.001). Incomplete coverage of the liver within the dual-energy field of view was most common in the obese subgroup (17.1%) compared with non-obese (0%) and pre-obese patients (4.1%).
Conclusion: DECT facilitates a 30.8% dose reduction over SECT in abdominal oncologic staging examinations. Employing dual-source scanner architecture, the risk for incomplete liver coverage increases in obese patients.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177533 | PMC |
| http://dx.doi.org/10.3390/diagnostics13091558 | DOI Listing |
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