Forgotten.

Nature

Published: May 2023

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http://dx.doi.org/10.1038/d41586-023-01556-2DOI Listing

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Stiffness after total knee arthroplasty (TKA) can lead to decreased function and patient dissatisfaction. Manipulation under anesthesia (MUA) is often performed to improve range of motion (ROM); however, there is no consensus on indications or timing. The purpose of this study was to compare clinical results and patient-reported outcome measures (PROMs) between patients who underwent MUA versus those with an uncomplicated postoperative course following primary TKA.

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Georgios Photeinos and his (1835) published in Ottoman Smyrna.

Pharmazie

December 2024

Department of the History of Pharmacy and Ethics, Erciyes University Faculty of Pharmacy, Kayseri, Turkey.

The , authored by Ottoman pharmacist Georgios Photeinos and published in 1835 in Smyrna (modern-day Izmir, T??rkiye), is a historically significant yet largely overlooked work in 19th-century pharmaceutical literature. At a time when modern pharmaceutical resources in Greek were scarce, Photeinos sought to address this gap by creating a comprehensive pharmacopoeia that extensively drew from the Austrian Pharmacopoeia, as well as French and Latin sources. Although he initiated the project around 1804, political upheavals delayed its completion by more than three decades.

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Individualized total knee arthroplasty achieves better functional results than off-the-shelf implants in patients undergoing personalized coronal alignment.

Knee

January 2025

IULS-University Institute for Locomotion and Sports, Pasteur 2 Hospital, University Côte d'Azur, Nice, France; ICARE Team, Côte d'Azur University, Inserm, CNRS, Valrose Institute of Biology, Nice, France. Electronic address:

Background: Several studies have demonstrated the interest in patient-specific custom cutting guides in total knee arthroplasty (TKA), but clinical improvement remains debated. The purpose of this study was to evaluate the functional outcomes (Forgotten Joint Score, FJS) of patients undergoing individualized TKA compared with those receiving off-the-shelf (OTS) implants, both using patient-specific cutting guides with personalized alignment over a minimum follow up period of 12 months. We hypothesized that individualized TKA demonstrates significantly better functional outcomes than OTS TKA (FJS and percentage of patients reaching the minimum clinically important difference).

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: Throat packs are widely used during orofacial surgery to reduce the frequency of postoperative nausea and vomiting (PONV). However, evidence supporting their use is mixed, with associated risks such as postoperative sore throat and the possibility of being forgotten in situ. : The aim of this study is to evaluate the effectiveness of throat packs in preventing PONV and postoperative sore throat during dental treatments under general anesthesia in children with special healthcare needs (SHCNs).

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