Through the analysis of the existing case data, this study explored the application effect of predictive nursing combined with bird nest nursing in children with hypoxic ischemic encephalopathy. The data of 120 children with hypoxic-ischemic encephalopathy admitted to our hospital from May 2019 to June 2021 were retrospectively analyzed, and they were divided into A ( = 40), B ( = 40) and C ( = 40) groups according to different nursing methods. Neonatal neurobehavioral assessment (NBNA), Canadian derivatives clearing corporation (CDCC) and Gesell Developmental Schedules (GDS) scores were compared among the three groups. Height, body mass, daily sleep time, milk intake and the occurrence of neurological sequelae were compared among the three groups. After intervention, the score of group A was higher than that of group B and C, with group B higher than group C (P<0.05). In addition, both mental developmental index (MDI) and psychomotive development index (PDI) of the three groups were all improved, in which Group A was the highest, followed by Group B (P<0.05). Scores of GDS of group A and B were higher than those of group C, while GDS of group A were higher than those of group B (P<0.05). After intervention, increases of height, body mass and milk intake in group A and B were greater than those in group C, while the increases of height and body mass in group A were better than those in group B (P<0.05).
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