Human descending aorta injury caused by brucellosis: A case report.

Medicine (Baltimore)

Department of Vascular Surgery, General Surgery Center, The First Hospital of Jilin University, Changchun, China.

Published: May 2023

AI Article Synopsis

  • Brucellosis is a widespread zoonotic disease, leading to significant cardiovascular complications and sometimes resulting in death, despite these issues being relatively rare.
  • Two patients with a history of brucellosis were treated for serious vascular problems (thoracic aortic ulcer and abdominal aortic pseudoaneurysm), successfully receiving aortic stent-graft implants after testing positive for IgG antibodies.
  • The study emphasizes that even after treatment for brucellosis, chronic vascular issues may persist, suggesting that individuals with a past diagnosis should have annual checks on their peripheral blood vessels.

Article Abstract

Background: Brucellosis is one of the most common zoonotic diseases in the world. Although cardiovascular complications of human brucellosis account for only 3% of morbidity, they are the leading cause of death. Peripheral vascular disease due to brucellosis is rare and under-reported in the literature.

Case Presentation: Two patients with previous brucellosis, both of whom had been treated with anti-brucellosis, were admitted to vascular surgery for thoracic aortic ulcer and abdominal aortic pseudoaneurysm, respectively, with positive IgG antibody to brucellosis and negative IgM antibody to brucellosis, tube agglutination test, and blood culture. These 2 patients were successfully treated with aortic stent-graft implantation and followed up for 8 and 10 weeks without complications.

Conclusions: Chronic damage to human blood vessels by brucellosis may not disappear with brucellosis treatment, and peripheral blood vessels should be examined annually in people previously diagnosed with brucellosis. Clinicians in related departments should pay attention to peripheral vascular complications of brucellosis.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10174350PMC
http://dx.doi.org/10.1097/MD.0000000000033764DOI Listing

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