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Can Surgery Be Proposed to Adolescent Idiopathic Scoliosis Patients With Structural Lumbar Curves Associated With Nonreducible Iliolumbar Angle?
J Pediatr Orthop
January 2025
Department of Pediatric Orthopaedic Surgery, Robert Debré University Hospital, Assistance Publique des Hôpitaux de Paris (AP-HP).
Background: Lower instrumented vertebra (LIV) selection for adolescent idiopathic scoliosis (AIS) with structural lumbar curves (Lenke 3, 5, and 6) remains debated. The iliolumbar angle (ILA) measurement is useful for assessing the lumbosacral junction flexibility. If it is nonreducible, surgeons need to make a difficult choice between a potential "imperfect" L4, associated with a residual lumbosacral curve, or a more distal fusion performed later in life due to poorer functional outcomes.
View Article and Find Full Text PDFCorrection: Strategic design of GalNAc-helical peptide ligands for efficient liver targeting.
Chem Sci
January 2025
Division of Organic Chemistry, National Institute of Health Sciences 3-25-26 Tonomachi Kawasaki Kanagawa 210-9501 Japan
[This corrects the article DOI: 10.1039/D4SC05606J.].
View Article and Find Full Text PDFCase Report: Neonatal onset intractable diarrhea and hypoproteinemia due to intestinal malrotation and chronic midgut volvulus.
Front Pediatr
January 2025
Children's Hospital, Fudan University, Shanghai, China.
Congenital diarrhea and enteropathies (CODEs) are a rare heterogeneous group of inherited disorders that typically present with severe chronic diarrhea during the first weeks of life. As a broad range of illnesses can present similarly in infants, establishing a definitive cause for CODEs is challenging. In this report, two infants were suspected to have CODE, with neonatal-onset chronic diarrhea and protein-losing enteropathy finally found to be due to intestinal malrotation and chronic midgut volvulus.
View Article and Find Full Text PDFGraded Anterior Partial-thickness Blepharotomy for the Correction of Idiopathic Unilateral Upper Eyelid Retraction: A Case Report and Literature Review.
Plast Reconstr Surg Glob Open
January 2025
From the Department of Plastic and Burn Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Idiopathic upper eyelid retraction is a rare ocular symptom characterized by abnormal upward displacement of the upper eyelid, often without any identifiable systemic disease. This condition not only affects the patient's appearance but may also have a certain impact on their daily life and mental health. We report a case of adult idiopathic unilateral upper eyelid retraction, and based on the patient's specific condition, we used graded anterior plate blepharoplasty for treatment.
View Article and Find Full Text PDFHealth-related quality of life associated with fatigue, physical activity and activity pacing in adults with chronic conditions.
BMC Sports Sci Med Rehabil
January 2025
Department of Sport Exercise and Rehabilitation, Northumbria University, Newcastle upon Tyne, UK.
Background: Fatigue and inactivity are linked to decreased health-related quality of life (HRQoL) in chronic conditions. A multidimensional approach to activity pacing may improve HRQoL by promoting physical activity (PA) and alleviating fatigue. Addressing fatigue across chronic conditions is crucial, especially when underlying causes are unknown.
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