We examined the relationship between the Bayes factor and the separation of credible intervals in between- and within-subject designs under a range of effect and sample sizes. For the within-subject case, we considered five intervals: (1) the within-subject confidence interval of Loftus and Masson (1994); (2) the within-subject Bayesian interval developed by Nathoo et al. (2018), whose derivation conditions on estimated random effects; (3) and (4) two modifications of (2) based on a proposal by Heck (2019) to allow for shrinkage and account for uncertainty in the estimation of random effects; and (5) the standard Bayesian highest-density interval. We derived and observed through simulations a clear and consistent relationship between the Bayes factor and the separation of credible intervals. Remarkably, for a given sample size, this relationship is described well by a simple quadratic exponential curve and is most precise in case (4). In contrast, interval (5) is relatively wide due to between-subjects variability and is likely to obscure effects when used in within-subject designs, rendering its relationship with the Bayes factor unclear in that case. We discuss how the separation percentage of (4), combined with knowledge of the sample size, could provide evidence in support of either a null or an alternative hypothesis. We also present a case study with example data and provide an R package 'rmBayes' to enable computation of each of the within-subject credible intervals investigated here using a number of possible prior distributions.
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http://dx.doi.org/10.3758/s13423-023-02295-1 | DOI Listing |
Medicine (Baltimore)
November 2024
Department of General Surgery, The Third Affiliated Hospital of Soochow University, Changzhou, China.
Miscarriage represents a prevalent yet insufficiently studied adverse pregnancy outcome. The definitive causal links between various pathogens and miscarriage remain to be established. To investigate the causal connections between pathogen infections and miscarriage, we utilized a two-sample bidirectional Mendelian randomization (MR) analysis.
View Article and Find Full Text PDFFront Psychol
December 2024
Department of Biological Psychology and Affective Science, Faculty of Human Sciences, University of Potsdam, Potsdam, Germany.
Introduction: It has long been known that highly arousing emotional single items are better recollected than low arousing neutral items. Despite the robustness of this memory advantage, emotional arousing events may not always promote the retrieval of source details (i.e.
View Article and Find Full Text PDFRisk Manag Healthc Policy
January 2025
Graduate Institute of Biomedical Informatics, College of Medical Science and Technology, Taipei Medical University, New Taipei City, 235603, Taiwan.
Purpose: As HF progresses into advanced HF, patients experience a poor quality of life, distressing symptoms, intensive care use, social distress, and eventual hospital death. We aimed to investigate the relationship between morality and potential prognostic factors among in-patient and emergency patients with HF.
Patients And Methods: A case series study: Data are collected from in-hospital and emergency care patients from 2014 to 2021, including their international classification of disease at admission, and laboratory data such as blood count, liver and renal functions, lipid profile, and other biochemistry from the hospital's electrical medical records.
J Transl Med
January 2025
Department of Rheumatology and Immunology, Peking University Third Hospital, No. 49, North Garden Road, Beijing, 100191, China.
Background: Sjogren syndrome (SS) is a chronic systemic autoimmune disease and its pathogenesis often involves the participation of numerous immune cells and inflammatory factors. Despite increased researches and studies recently focusing on this area, it remains to be fully elucidated. We decide to incorporate genetic insight into investigation of the causal link between various immune cells, inflammatory factors and pathogenesis of Sjogren syndrome (SS).
View Article and Find Full Text PDFStrong sex differences exist in sleep phenotypes and also cardiovascular diseases (CVDs). However, sex-specific causal effects of sleep phenotypes on CVD-related outcomes have not been thoroughly examined. Mendelian randomization (MR) analysis is a useful approach for estimating the causal effect of a risk factor on an outcome of interest when interventional studies are not available.
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