During meningitis, sensory neurons detect bacterial toxins and metabolites. Early activation of pain receptors suppresses host defense in the meninges while, later, taste receptors amplify inflammation in the spinal cord. Is a neuroimmune axis a clue to new treatments?
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http://dx.doi.org/10.1016/j.chom.2023.04.006 | DOI Listing |
Shanghai Kou Qiang Yi Xue
October 2024
Department of Stomatology, Nanjing Gaochun People's Hospital. Nanjing 211300, China. E-mail:
Purpose: To explore the effects of personalized oral stents in intensity-modulated radiation therapy (IMRT) treatment.
Methods: Totally 108 patients with nasopharyngeal carcinoma treated with IMRT at Nanjing Gaochun People's Hospital from January 2021 to December 2023 were selected. Using a random number table method, the patients were divided into experimental group (n=54) using personalized oral stents and control group (n=54) using simple mouthpieces.
Food Chem
December 2024
Department of Chemistry, North Eastern Regional Institute of Science and Technology, Nirjuli, Itanagar, Arunachal Pradesh 791109, India. Electronic address:
Coriander (Coriandrum sativum L.) is a nutraceutically renowned annual herb from Apiaceae family and used in cuisines in different countries in different ways to enhance the tastes, flavour and nutritional values of foods. Fruit (seed) has several medicinally valuable chemical components viz.
View Article and Find Full Text PDFJ Neurochem
January 2025
Department of Oral Physiology, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
Different taste cells express unique cell-type markers, enabling researchers to distinguish them and study their functional differentiation. Using single-cell RNA-Seq of taste cells in mouse fungiform papillae, we found that Cellular Communication Network Factor 3 (Ccn3) was highly expressed in Type III taste cells but not in Type II taste cells. Ccn3 is a protein-coding gene involved in various biological processes, such as cell proliferation, angiogenesis, tumorigenesis, and wound healing.
View Article and Find Full Text PDFLasers Med Sci
December 2024
State University of Paraíba, R. Baraúnas, 351, Bairro Universitário, Campina Grande, PB, 58429-500, Brazil.
The aim of this study was to investigate the scientific evidence regarding the effectiveness of modified-ILIB (intravascular laser irradiation of blood) in the control of systemic conditions and/or oral changes during dental care. This systematic literature review study aimed to answer the question, "Is modified-ILIB an effective adjuvant therapy in the control of systemic conditions and/or oral changes in children and adults during dental treatment?". The protocol for this systematic review was registered in the PROSPERO database under number CRD42023493800.
View Article and Find Full Text PDFPsychooncology
December 2024
Department of Psychiatry & Behavioral Sciences, School of Medicine, Stanford University, Stanford, California, USA.
Taste disturbances are prominent side effects of antineoplastic medications and contribute to morbidity and quality-of-life impairment. Few treatment options are available for antineoplastic-related taste disorders. Hypnosis has been found to be effective for a variety of symptoms in the cancer setting, including insomnia, pain, mood disorders and anxiety.
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