AI Article Synopsis
- - COVID-19, caused by the SARS-CoV-2 virus, has become a persistent global health crisis, prompting a study in a tertiary hospital in Peru to explore mortality factors among hospitalized patients.
- - The study analyzed 297 COVID-19 patients, revealing that most were women with a mean age of nearly 64 years; common comorbidities included hypertension and diabetes, with survival probabilities decreasing significantly over a week of ICU care.
- - Key mortality risk factors identified included older age, male gender, tachypnea, low blood pressure, low oxygen levels, renal issues, and high levels of inflammatory markers like IL-6 and D-dimer, highlighting a mortality rate of 51.18 per 100 patients.
Article Abstract
Introduction: COVID-19 caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has spread worldwide, becoming a long-term pandemic.
Objectives: To analyze the factors associated with mortality in patients hospitalized for COVID-19 in a tertiary hospital in the Lambayeque region of Peru.
Methods: A retrospective cohort study of patients with a diagnosis of COVID-19, hospitalized in a hospital in northern Peru, was conducted from March to September 2020.
Results: Of the 297 patients studied, 69% were women, the mean age was 63.99 years (SD = ±15.33 years). Hypertension was the most frequent comorbidity (36.67%), followed by diabetes mellitus (24.67%) and obesity (8.33%). The probability of survival at 3 days of ICU stay was 65.3%, at 7 days 24.2%, and 0% on day 14. Risk factors associated with mortality in patients hospitalized for COVID-19 are age, male sex, tachypnea, low systolic blood pressure, low peripheral oxygen saturation, impaired renal function, elevated IL-6 and elevated D-dimer.
Conclusions: Mortality in hospitalized patients with COVID-19 was 51.18 per 100 persons, Mortality was found to be associated with hypertension, type of infiltrating, and sepsis.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10174592 | PMC |
| http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0285133 | PLOS |
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