This article deals with comparative results of the use of modern examination methods in the early diagnosis of kidney cancer, in determining the stage of invasion, and in choosing strategies for its radical treatment. The research work included 170 patients who were treated in department of urology of Azerbaijan Medical University with the diagnosis of kidney cancer from 2006-2016. The age range of patients was between 23-82 (average 61.7), 93(54.7%) were male and 77 (45.3%) were female. According to the application of radiation examinations, we have divided the patients into two groups who are under our observation. Only ultrasound examination was applied to the patients included in the first group for diagnostic purposes, while modern radiation examinations were applied comprehensively to the patients included in the second group. 63 of the patients included in the first group were satisfied with only the results of the ultrasound examination and the appropriate type of treatment was prescribed without additional examinations. In 107, examinations were applied in a complex manner (USM, CT, MRI). According to the results of our research, the response of USM to the stages of kidney cancer in determining the stage of process invasion is T1-97.9±1.2%, T2-94.2±2.3%, T3-92.2±2.5% %, T4-98.0±1.1%, and its sensitivity is 89.7±5.7% in T1 stage, 87.9±4.0% in T2 stage, 87.3±4.5% in T3 stage, It was 85.0±8.0.9% for T4 stage. In patients with kidney cancer, the diagnostic possibility of ultrasound examination and determination of the stage of invasion was 90.5% correct and 9.5% incorrect. 90.4% correct in the placement of the tumor, 9.6% incorrect, 86.9% correct in determining the size of the tumor tissue, 13.1% incorrect, 92.6% correct in 7.4% in determining the direction of development intrarenal wrong, extrarenal development is completely consistent. Specificity of computed tomography by stages in determining the degree of local spread of the process in patients with kidney cancer: T1-98.6±1.4%, T2-91.7±4.0%, T3-84.5±4.8%, T4-97.3±1.9% sensitivity and T1-90.9±8.7%, T2-80.6±6.6%, T3-80.8±7.7%, T4-72.7±13 it has been like this. Our retrospective review revealed that the screenings related to the stage of cancer development were satisfactory and there was no need for additional more complex and expensive screenings. In other patients (T3-T4), conducting preoperative thoracoabdominal CT and MRI examinations was considered important from the point of view of obtaining effective results in order to put an end to the controversial issues arising in the diagnosis and selection of radical treatment.

Download full-text PDF

Source

Publication Analysis

Top Keywords

kidney cancer
24
diagnosis kidney
12
cancer determining
12
determining stage
12
stage invasion
12
radical treatment
12
ultrasound examination
12
patients included
12
stage
9
patients
9

Similar Publications

Background: Disturbances in DNA damage repair may lead to cancer. SIRT1, an NAD+-dependent deacetylase, plays a crucial role in maintaining cellular homeostasis through the regulation of processes such as histone posttranslational modifications, DNA repair, and cellular metabolism. However, a comprehensive exploration of SIRT1's involvement in pan-cancer remains lacking.

View Article and Find Full Text PDF

Introduction: The mortality rate for liver cancer is extremely high but clinical treatments have not made much progress, so it is necessary to develop anticancer agents with lower toxicities and more effective liver-targeting drug delivery systems (LTDDSs). At present, LTDDSs mediated by the asialoglycoprotein receptor (ASGPR) show excellent effects at improving the liver-targeting and antitumor effects of drugs. However, the galactosyl ligands are typically prepared by chemical synthesis and have some shortcomings.

View Article and Find Full Text PDF

Purpose: Smoking is a well-established risk factor for kidney cancer. Analyzing the latest global spatio-temporal trends in the kidney cancer burden attributable to smoking is critical for informing effective public health policies.

Methods: Using data from the 2021 GBD database, we examined deaths, disability-adjusted life years (DALYs), and age-standardized rate (ASR) of kidney cancer attributable to smoking across global, regional, and national levels.

View Article and Find Full Text PDF

Introduction Ki-67 is a proliferation marker that may correlate with tumor grade in breast cancer. This study explores the association between Ki-67 expression levels and tumor grade in breast cancer patients. Materials and methods This cross-sectional study analyzed Ki-67 expression in tumor samples from 280 breast cancer patients.

View Article and Find Full Text PDF

Introduction: /GI.1 and GI.2 cause severe Rabbit Haemorrhagic Disease, and immune processes are among the important pathomechanisms of the disease.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!