JGP study (Gada et al. 2023. J. Gen. Physiol. https://doi.org/10.1085/jgp.202213255) reveals that the membrane lipid PI(4,5)P2 alters the activity of NaV1.4 channels by modulating their gating behavior.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182773PMC
http://dx.doi.org/10.1085/jgp.202313402DOI Listing

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