Three new lanostane-type triterpenes from the epidermis of .

Nat Prod Res

Department of Natural Products Chemistry, School of Pharmacy, China Medical University, Shenyang, People's Republic of China.

Published: September 2024

is commonly used as a traditional Chinese medicine for its diuretic, tonifying, and invigorating effects on the spleen. However, the epidermis of is discarded as scrap during harvesting because of its low price, resulting in a great waste of resources and environmental pollution. In this work, the epidermis of was studied and three new lanostane triterpenoids were isolated. The structures were determined using NMR and HRESIMS, with absolute configurations established by comparison of the calculated and experimental ECD spectra. The three new compounds were evaluated for their antimicrobial activities against , , and . None of the tested compounds showed inhibition against these three strains of indicator microbes at a concentration of 128 μg/ml. This study provides a reference for further medicinal development and the utilization of the epidermis of .

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http://dx.doi.org/10.1080/14786419.2023.2210737DOI Listing

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