Demand side management (DSM) is one of the trending economic strategies which shifts the elastic demand to the off-peak hours from the peak hours so as to reduce the overall generation cost of the system. The work done in this paper can be categorized in three phases. In the first phase, various wind speed to power conversion mathematical models available in literature are analysed to find out the one with maximum level of wind penetration. For second phase, an economic DSM strategy is implemented to restructure the forecasted load demand model for various participation levels. In the final phase the cost-effective optimization of two microgrid distribution systems are percolated. As an optimization tool, novel hybrid CSAJAYA has been used to carry on the study. Different types of grid participating and pricing strategies along with valve point loading effect and wind energy uncertainty are considered to amplify the complexity and practicality of the study. The generation costs reduced from 3 to 5% when the forecasted demand was reformed with 20% DSM participation for both the test systems. A detailed comparison with the results from various optimization tools studied confirms the effectiveness of the proposed hybrid approach. The hybrid optimization tool presented in this paper performs better in terms of central tendencies, nonparametric statistical analysis, and algorithm execution time.
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http://dx.doi.org/10.1016/j.isatra.2023.04.027 | DOI Listing |
J Med Internet Res
January 2025
Department of Computer Science and Software Engineering, United Arab Emirates University, Al Ain, United Arab Emirates.
Background: Neuroimaging segmentation is increasingly important for diagnosing and planning treatments for neurological diseases. Manual segmentation is time-consuming, apart from being prone to human error and variability. Transformers are a promising deep learning approach for automated medical image segmentation.
View Article and Find Full Text PDFLangmuir
January 2025
School of Chemical Engineering, The University of Queensland, Brisbane, QLD 4072, Australia.
Ofloxacin, a commonly prescribed antibiotic, raises serious environmental concerns due to its persistence in aquatic systems. This study offers new insights into the environmental behavior of ofloxacin and its interactions with carbon-based adsorbents with the aim of enhancing our understanding of its removal mechanisms via adsorption processes. Using a comprehensive computational approach, we analyzed the speciation, pK values, and solubility of ofloxacin across various pH conditions, accounting for all four microspecies, including the often-overlooked neutral form.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
Department of Environmental Engineering, Kwangwoon University, Seoul 01897, Republic of Korea.
The advancement of highly efficient and cost-effective electrocatalysts for electrochemical water splitting, along with the development of triboelectric nanogenerators (TENGs), is crucial for sustainable energy generation and harvesting. In this study, a novel hybrid composite by integrating graphitic carbon nitride (GCN) with an earth-abundant FeMg-layered double hydroxide (LDH) (GCN@FeMg-LDH) was synthesized by the hydrothermal approach. Under controlled conditions, with optimized concentrations of metal ions and GCN, the fabricated electrode, GCN@FeMg-LDH demonstrated remarkably low overpotentials of 0.
View Article and Find Full Text PDFJ Med Chem
January 2025
College of Chemistry, Zhengzhou University, Zhengzhou 450001, China.
The P2YR is activated by UDP and UDP glucose and is involved in many human inflammatory diseases. Based on the molecular docking analysis of currently reported P2YR antagonists and the crystallographic overlap study between PPTN and compound , a series of 3-substituted 5-amidobenzoate derivatives were designed, synthesized, and identified as promising P2YR antagonists. The optimal compound (methyl 3-(1-benzo[]imidazol-2-yl)-5-(2-(-tolyl) acetamido)benzoate, IC = 0.
View Article and Find Full Text PDFRSC Adv
January 2025
Institute of Chemistry, Vietnam Academy of Science and Technology (VAST) 18 Hoang Quoc Viet, Cau Giay Hanoi Vietnam
Podophyllotoxin, along with its numerous derivatives and related compounds, is well known for its broad-spectrum pharmacological activity, especially for anticancer potential. In this study, several isatin-podophyllotoxin hybrid compounds were successfully synthesized with good yields through microwave-prompted three-component reactions of 2-amino-1,4-naphthoquinone, various substituted isatins, and tetronic acid. Their cytotoxicity was assessed against four types of human cancer cell lines, HepG2 (hepatoma carcinoma), MCF7 (breast cancer), A549 (non-small lung cancer), and KB (epidermoid carcinoma), alongside nontumorigenic HEK-293 human embryonic kidney cells.
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