Objective: To assess the effectiveness of low contrast volume (LCV) chest CT performed with multiple contrast agents on multivendor CT with varying scanning techniques.
Methods: The study included 361 patients (65 ± 15 years; M: F 173:188) who underwent LCV chest CT on one of the six 64-256 detector-row CT scanners using single-energy (SECT) or dual-energy (DECT) modes. All patients were scanned with either a fixed-LCV (LCVf, n = 103) or weight-based LCV (LCVw, n = 258) protocol. Two thoracic radiologists independently assessed all LCV CT and patients' prior standard contrast volume (SCV, n = 263) chest CT for optimality of contrast enhancement in thoracic vasculature, cardiac chambers, and in pleuro-parenchymal and mediastinal abnormalities. CT attenuations were recorded in the main pulmonary trunk, ascending, and descending thoracic aorta. To assess the interobserver agreement, pulmonary arterial enhancement was divided into two groups: optimal or suboptimal.
Results: There was no significant difference among patients' BMI (p = 0.883) in the three groups. DECT had a significantly higher aortic arterial enhancement (250 ± 99HU vs 228 ± 76 HU for SECT, p < 0.001). Optimal enhancement was present in 558 of 624 chest CT (89.4%), whereas 66 of 624 chest CT with suboptimal enhancement was noted in 48 of 258 LCVw (18.6%) and 14 of 103 LCVf (13.6%). Most patients with suboptimal enhancement with LCVw injection protocol were overweight/obese (30/48; 62.5%), (p < 0.001).
Conclusion: LCV chest CT can be performed across complex multivendor, multicontrast media, multiscanner, and multiprotocol CT practices. However, LCV chest CT examinations can result in suboptimal contrast enhancement in patients with larger body habitus.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.acra.2023.03.020 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Thoracic cavity remodeling and pulmonary function change after chest wall resection.
J Thorac Dis
May 2024
Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul, Republic of Korea.
Article Synopsis
- Chest wall resection (CWR) is a surgical procedure aimed at treating serious chest conditions, but its impact on lung function and thoracic cavity volume (TCV) has not been widely studied.
- A review of 45 patients who underwent CWR revealed significant long-term decreases in pulmonary function, specifically in forced vital capacity (FVC) and forced expiratory volume (FEV), but no significant changes in TCV or the ratio of FEV/FVC.
- The extent of rib resection influenced outcomes, with patients undergoing more extensive resections (≥3 ribs) experiencing greater decreases in lung function compared to those with fewer ribs resected.
Low Contrast Volume Protocol in Routine Chest CT Amid the Global Contrast Shortage: A Single Institution Experience.
Acad Radiol
December 2023
Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, 75 Blossom Court, Boston, Massachusetts, 02114. Electronic address:
Objective: To assess the effectiveness of low contrast volume (LCV) chest CT performed with multiple contrast agents on multivendor CT with varying scanning techniques.
Methods: The study included 361 patients (65 ± 15 years; M: F 173:188) who underwent LCV chest CT on one of the six 64-256 detector-row CT scanners using single-energy (SECT) or dual-energy (DECT) modes. All patients were scanned with either a fixed-LCV (LCVf, n = 103) or weight-based LCV (LCVw, n = 258) protocol.
Multimarker Analysis of Serially Measured GDF-15, NT-proBNP, ST2, GAL-3, cTnI, Creatinine, and Prognosis in Acute Heart Failure.
Circ Heart Fail
January 2023
Department of Cardiology, Thorax Center, Erasmus MC, University Medical Center Rotterdam, the Netherlands (MT.G., L.C.v.V., I.K., K.M.A., O.C.M., E.B.).
Background: Studies on serially measured GDF-15 (growth differentiation factor 15) in acute heart failure (HF) are limited. Moreover, several pathophysiological pathways contribute to HF. Therefore, we aimed to explore the (additional) prognostic value of serially measured GDF-15 using a multi-marker approach to more accurately predict HF risk.
View Article and Find Full Text PDFA Young Female Case of Polyarteritis Nodosa Presenting With Multisystem Involvement and Acute Abdomen: A Case Report.
Cureus
December 2021
General Surgery, Shri Sathya Sai Medical College and Research Institute, Ammapettai, IND.
Polyarteritis nodosa (PAN) is a medium vessel vasculitis that affects multiple organ systems except the lungs. It is transmural segmental necrotizing inflammation associated with fibrinoid necrosis. Hepatitis B virus (HBV) infection is strongly associated with PAN.
View Article and Find Full Text PDFThe Model for Early COvid-19 Recognition (MECOR) Score: A Proof-of-Concept for a Simple and Low-Cost Tool to Recognize a Possible Viral Etiology in Community-Acquired Pneumonia Patients during COVID-19 Outbreak.
Diagnostics (Basel)
August 2020
Department of Medical, Surgical and Health Sciences, University of Trieste, 34151 Trieste, Italy.
This study aims to assess the peripheral blood cell count "signature" of Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2) to discriminate promptly between COronaVIrus Disease 19 (COVID-19) and community-acquired pneumonia (CAP). We designed a retrospective case-control study, enrolling 525 patients (283 COVID-19 and 242 with CAP). All patients had a fever and at least one of the following signs: cough, chest pain, or dyspnea.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!