Preparing functional genomic (FG) data with diverse assay types and file formats for integration into analysis workflows that interpret genome-wide association and other studies is a significant and time-consuming challenge. Here we introduce hipFG, an automatically customized pipeline for efficient and scalable normalization of heterogenous FG data collections into standardized, indexed, rapidly searchable analysis-ready datasets while accounting for FG datatypes (e.g., chromatin interactions, genomic intervals, quantitative trait loci).

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168270PMC
http://dx.doi.org/10.1101/2023.04.21.537695DOI Listing

Publication Analysis

Top Keywords

hipfg high-throughput
4
high-throughput harmonization
4
harmonization integration
4
integration pipeline
4
pipeline functional
4
functional genomics
4
genomics data
4
data preparing
4
preparing functional
4
functional genomic
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!