Four new iridoid glycosides from the roots of .

J Asian Nat Prod Res

State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.

Published: March 2024

Four new iridoid glycosides (-), rehmaglutosides L-O, were isolated from the air-dried roots of . Their structures were established from the spectroscopic data obtained and by chemical evidence. The known mellittoside () and ajugol () were also obtained in the current investigation, and the structure of mellittoside was unequivocally defined using X-ray diffraction data. Compounds - were tested for their cytotoxicity against five human tumor cell lines and proliferation effects on .

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http://dx.doi.org/10.1080/10286020.2023.2202856DOI Listing

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