Haloperidol is frequently used as first-line treatment for delirium. The Swiss Smarter medicine campaign recommends to favor non-pharmacological interventions and treatment of the underlying causes, in order to limit the use of haloperidol. When antipsychotics are necessary, they should be prescribed cautiously, taking into account contraindications and potential side effects. This article emphasizes the importance of history taking in patient with delirium before prescribing haloperidol.
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http://dx.doi.org/10.53738/REVMED.2023.19.826.920 | DOI Listing |
Eur J Pediatr
November 2024
Child and Adolescent Psychiatry Unit, Neuroscience and Human Genetics Department, Meyer Children's Hospital IRCCS 50139, Florence, Italy.
PLoS Biol
July 2024
Biological Psychology of Decision Making, Institute of Experimental Psychology, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
In everyday life, we encounter situations that require tradeoffs between potential rewards and associated costs, such as time and (physical) effort. The literature indicates a prominent role for dopamine in discounting of both delay and effort, with mixed findings for delay discounting in humans. Moreover, the reciprocal antagonistic interaction between dopaminergic and cholinergic transmission in the striatum suggests a potential opponent role of acetylcholine in these processes.
View Article and Find Full Text PDFCochrane Database Syst Rev
July 2024
Epicentre, Paris, France.
Background: Schizophrenia is often a severe and disabling psychiatric disorder. Antipsychotics remain the mainstay of psychotropic treatment for people with psychosis. In limited resource and humanitarian contexts, it is key to have several options for beneficial, low-cost antipsychotics, which require minimal monitoring.
View Article and Find Full Text PDFSupport Care Cancer
June 2024
Interdisciplinary Center for Palliative Medicine, University Hospital Wuerzburg, Würzburg, Germany.
Purpose: We assumed that in Palliative Care, even in common clinical situations, the choice of drugs differs substantially between physicians. Therefore, we assessed the practice of pharmaceutical treatment choices of physicians for cancer pain and opioid-induced nausea and vomiting (OINV) and the rationale for their choices.
Methods: An online survey was conducted with physicians covering the following domains: i) Cancer pain therapy: non-opioids in addition to opioids: choice of drug ii) prevention of OINV: choice of drug and mode of application.
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