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Objective: ADHD is one of the most common neurodevelopmental disorders, seen in children and adolescents, and is often treated with various pharmacological agents, especially methylphenidate. There are differing opinions in the literature regarding the cardiovascular safety of long-term methylphenidate use. Studies suggest that the drug may increase the risk of hypertension, myocardial infarction, ventricular arrhythmia, sudden cardiac death, cardiomyopathy, heart failure (HF), pulmonary hypertension, and stroke.
View Article and Find Full Text PDFCardiovascular problems in rabbits in reference to hypothyroidism - a four-year retrospective study.
Pol J Vet Sci
December 2024
Department of Epizootiology and the Clinic of Infectious Diseases, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, Głęboka 30, 20-612 Lublin, Poland.
The effects of T4 are mainly manifested by positive ino- and chronotropism. The syndrome accompanying hypothyroidism in rabbits (impaired myocardial contractility and reduced ejection capacity) is caused by a deficiency of thyroid hormones - especially T4. The study group consisted of a total of 41 animals: 15 males and 26 females, ranging in age from 2 months to 8 years, with echocardiogram showing reduced fractional shortening (<30%), with normal results of heamatological and biochemical tests.
View Article and Find Full Text PDFCan early diaphragm dysfunction in critically ill ventilated patients predict clinical outcomes? A pilot study.
Med Ultrason
December 2024
Intensive Care Department, Centro Hospitalar Universitário Lisboa Norte, Faculdade de Medicina, Universidade de Lisboa, Lisbon.
Aim: Diaphragm dysfunction (DD) is a keystone factor in difficult weaning from invasive mechanical ventilation (IMV). Diaphragm ultrasound (DUS) is the preferred method for the evaluation of diaphragm function in the Intensive Care Unit (ICU) setting, namely through the diaphragm thickening fraction (DTF). However, its potential role in the decision-making process of mechanical ventilation weaning is yet to be established.
View Article and Find Full Text PDFDifferences in the Impact of Left Ventricular Outflow Tract Obstruction on Intraventricular Pressure Gradient in Feline Hypertrophic Cardiomyopathy.
Animals (Basel)
November 2024
Veterinary Teaching Hospital, Tokyo University of Agriculture and Technology, Fuchu 183-0054, Tokyo, Japan.
Article Synopsis
- Hypertrophic cardiomyopathy (HCM) is a common heart condition in cats, leading to heart failure due to diastolic dysfunction, and can be classified as obstructive or non-obstructive based on whether there's an obstruction in the outflow tract.
- Recent research focused on using color M-mode (CMM) to measure intraventricular pressure differences (IVPD) and create an intraventricular pressure gradient (IVPG) index to assess diastolic impairment non-invasively in cats with obstructive HCM.
- The findings indicated that while there was no severe left atrial enlargement in cats with obstructive HCM, the IVPG was significantly higher compared to control cats, suggesting elevated left
[Analysis of ultrasonographic measurements of inferior vena cava and abdominal aorta diameters in neonates].
Zhonghua Er Ke Za Zhi
December 2024
Department of Neonatology, the First People's Hospital of Kunshan, Kunshan215300, China.
To analyze the ultrasonographic measurements of inferior vena cava (IVC) and abdominal aorta in healthy full-term neonates throughout the early postnatal period. Prospective observational study was conducted. A total of 132 healthy full-term neonates, who were born at the Kunshan First People's Hospital between May 1 and August 30, 2023, were enrolled as the study subjects.
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