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Infectiological Outcome of Total Hip and Total Knee Arthroplasty in Post-Traumatic and Primary Osteoarthritis.
Antibiotics (Basel)
December 2024
Department of Orthopedics, Trauma and Plastic Surgery, University Hospital Leipzig, 04317 Leipzig, Germany.
: The objective of this study was to compare infection rates, pathogen species detection and antimicrobial susceptibility testing in patients with total hip arthroplasty (THA) and total knee arthroplasty (TKA) following post-traumatic osteoarthritis (PTOA) and primary osteoarthritis (POA). : Patients undergoing both THA and TKA were significantly more likely to have a PJI after PTOA than after POA (THA: 2.5% vs.
View Article and Find Full Text PDFPrevention and Modern Strategies for Managing Methicillin-Resistant Staphylococcal Infections in Prosthetic Joint Infections (PJIs).
Antibiotics (Basel)
December 2024
Department of Microbiology, Faculty of Medicine, Wroclaw Medical University, Tytusa Chalubinskiego 4, 50-376 Wroclaw, Poland.
Periprosthetic joint infections (PJIs) are a dangerous complication of joint replacement surgeries which have become much more common in recent years (mostly hip and knee replacement surgeries). Such a condition can lead to many health issues and often requires reoperation. Staphylococci is a bacterial group most common in terms of the pathogens causing PJIs.
View Article and Find Full Text PDFSelective outcome reporting concerning antibiotics and third molar surgery.
Clin Oral Investig
January 2025
Department of Oral and Maxillofacial Surgery, School of Dentistry, University of São Paulo, Av. Prof. Lineu Prestes, 2227 - Cidade Universitária, São Paulo, 05508-000, Brazil.
Objectives: This study evaluates the selective outcome reporting (SOR) in clinical trials on antibiotic use in third molar surgeries. It explores how SOR may bias results and affect systematic reviews, potentially leading to misinterpretations of intervention efficacy.
Materials And Methods: A search was conducted on "ClinicalTrials.
The identification of low-pathogenic bacteria on removed spinal implants and implications for antimicrobial prophylaxis.
Brain Spine
December 2024
Department of Neurosurgery, Ruprecht-Karls-University Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.
Article Synopsis
- The study examines the role of low-pathogenic bacteria from removed spinal implants and evaluates the effectiveness of single-dose antibiotics before surgery.
- A retrospective analysis of 93 patients found that bacterial presence in loosened implants (41%) was not significantly different from non-loosened ones (27%), highlighting a possible link between bacterial resistance and antibiotic choice.
- The results indicate a need for reevaluating current antibiotic prophylaxis due to the prevalence of both sensitive and resistant bacteria, emphasizing the importance of further research on low-virulence bacteria in non-loosened implants.
Perioperative anaphylaxis manifesting as cardiac arrest during cardiac surgery.
Allergy Asthma Proc
January 2025
Perioperative anaphylaxis is a serious entity with high morbidity and mortality. Perioperative anaphylaxis can be caused by any of the multitude of medications and substances used in anesthesia and surgery, and the most common causes include neuromuscular blocking agents, antibiotics, antiseptics, latex, and dyes. The differential diagnosis of perioperative anaphylaxis is wide from both an immunologic and a nonimmunologic standpoint.
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