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| http://dx.doi.org/10.1016/j.vaa.2023.03.004 | DOI Listing |
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National early warning score 2 plus non-invasive capnography and perfusion index to estimate poor outcomes in emergency departments.
Am J Emerg Med
January 2025
Faculty of Medicine, Universidad de Valladolid, Valladolid, Spain; Emergency Department, Hospital Clínico Universitario, Gerencia Regional de Salud de Castilla y León, Valladolid, Spain.
Background: The study of the inclusion of new variables in already existing early warning scores is a growing field. The aim of this work was to determine how capnometry measurements, in the form of end-tidal CO2 (ETCO2) and the perfusion index (PI), could improve the National Early Warning Score (NEWS2).
Methods: A secondary, prospective, multicenter, cohort study was undertaken in adult patients with unselected acute diseases who needed continuous monitoring in the emergency department (ED), involving two tertiary hospitals in Spain from October 1, 2022, to June 30, 2023.
[Research progress on the application of end-tidal carbon dioxide monitoring in prehospital emergency care].
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
December 2024
Department of Emergency Medicine, Shenzhen University General Hospital, Shenzhen 518071, Guangdong, China.
Prehospital emergency care is the primary stage in the treatment of critically ill patients, where efficient and accurate monitoring methods are crucial for patient survival and prognosis. End-tidal carbon dioxide (EtCO) monitoring is a real-time, non-invasive method that can sensitively capture the status of respiratory, circulatory, and metabolic functions, particularly in the urgent and complex pre-hospital environment, a immediate detection and non-invasive method, can sensitively capture the respiratory, circulatory, and metabolic status of patients. It provides valuable guidance for rapid decision-making and precise interventions.
View Article and Find Full Text PDFValidation of a method for estimating pulmonary dead space in ventilated beagles to correct exhaled propofol concentration in mixed air.
BMC Vet Res
January 2025
Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, China.
Background: Mixed exhaled air has been widely used to determine exhaled propofol concentrations with online analyzers, but changes in dead space proportions may lead to inaccurate assessments of critical drug concentration data. This study proposes a method to correct propofol concentration in mixed air by estimating pulmonary dead space through reconstructing volumetric capnography (Vcap) from time-CO and time-volume curves, validated with vacuum ultraviolet time-of-flight mass spectrometry (VUV-TOF MS).
Methods: Existing monitoring parameters, including time-volume and time-CO curves, were used to determine Vcap.
Noninvasive estimation of PaCO from volumetric capnography in animals with injured lungs: an Artificial Intelligence approach.
J Clin Monit Comput
December 2024
Department of Critical Care, Hospital Universitario de La Princesa, Madrid, Spain.
To investigate the feasibility of non-invasively estimating the arterial partial pressure of carbon dioxide (PaCO) using a computational Adaptive Neuro-Fuzzy Inference System (ANFIS) model fed by noninvasive volumetric capnography (VCap) parameters. In 14 lung-lavaged pigs, we continuously measured PaCO with an optical intravascular catheter and VCap on a breath-by-breath basis. Animals were mechanically ventilated with fixed settings and subjected to 0 to 22 cmHO of positive end-expiratory pressure steps.
View Article and Find Full Text PDFEvaluating the utility of end-tidal CO as a predictor of mortality in trauma victims: A systematic review and meta-analysis.
Am J Surg
December 2024
Department of Surgery, Southern Illinois University School of Medicine, Carbondale, IL, USA. Electronic address:
Article Synopsis
- Capnography, specifically end-tidal CO (ETCO) and the arterial CO-ETCO gap (PaCO-ETCO), is effective in predicting mortality in trauma patients.
- A systematic review of 17 studies involving 3,445 trauma patients revealed significant differences in ETCO levels and PaCO-ETCO gaps between survivors and those who did not survive.
- Low ETCO readings (below 30.2 mmHg) and wide PaCO-ETCO gaps correlate with worse outcomes, indicating that these measurements can guide more aggressive treatment for critical patients.
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