Stable propagation of multifilament arrays in transparent bulk media with adjustable separation distances between adjacent child filaments has always been desired for advanced manufacturing. Here, we report on the generation of an ionization-induced volume plasma grating (VPG) by the interaction of two batches of noncollinearly propagating arrays of multiple filaments (AMF). The VPG can externally arrange the propagation of the pulses along regular plasma waveguides via spatial reconstruction of electrical fields, which is compared with the self-formation of randomly distributed multiple filamentation originated from noises. The separation distances of filaments in VPG are controllable by readily changing the crossing angle of the excitation beams. In addition, an innovative method to efficiently fabricate multidimensional grating structures in transparent bulk media through laser modification using VPG was demonstrated.
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http://dx.doi.org/10.1364/OE.480622 | DOI Listing |
Pharmaceutics
December 2024
PerMed Research Group, Center for Health Technology and Services Research (CINTESIS), Rua Doutor Plácido da Costa, 4200-450 Porto, Portugal.
Background: Salbutamol, a short-acting β-agonist used in asthma treatment, is available in multiple formulations, including inhalers, nebulizers, oral tablets, and intravenous, intramuscular, and subcutaneous routes. Each formulation exhibits distinct pharmacokinetic (PK) and pharmacodynamic (PD) profiles, influencing therapeutic outcomes and adverse effects. Although asthma management predominantly relies on inhaled salbutamol, understanding how these formulations interact with patient-specific characteristics could improve personalized medicine approaches, potentially uncovering the therapeutic benefits of alternative formulations for an individual patient.
View Article and Find Full Text PDFLife (Basel)
December 2024
Department of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing 100069, China.
Prediabetes, a state between normoglycemia and diabetes, is increasingly affecting population health; thus, it should not be overlooked. This systematic review and meta-analysis aimed to explore the efficacy of aerobic exercise on blood glucose indicators among those with prediabetes. Five databases, including PubMed, Embase, the Cochrane Library, Web of Science, and CINAHL, were searched up to September 2024 to identify randomized controlled trials measuring the effect of aerobic exercise on blood glucose levels among individuals with prediabetes.
View Article and Find Full Text PDFMaterials (Basel)
January 2025
School of Aerospace Engineering, Xi'an Jiaotong University, West Xianning Road 28, Xi'an 710049, China.
The aim of this paper is to investigate the effect of TiC addition on the microstructure, microhardness, and wear resistance of the medium-entropy alloy Co37Cr28Ni31Al2Ti2, which is suitable for applications in aerospace, automotive, and energy industries due to its high strength and wear resistance. The samples containing 0, 10, 20, and 40 wt.% of TiC were synthesized.
View Article and Find Full Text PDFInt J Mol Sci
January 2025
State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, College of Life Science, Inner Mongolia University, Hohhot 010070, China.
N6-methyladenosine (m6A) modification is a key methylation modification involved in reproductive processes. gene editing (MT) in cattle is known to enhance muscle mass and productivity. However, the changes in m6A modification in MT bull sperm remain poorly understood.
View Article and Find Full Text PDFBiomedicines
January 2025
Department of Mechanical Engineering, National Yang Ming Chiao Tung University, Hsinchu 300, Taiwan.
: Cold atmospheric plasma (CAP) has been demonstrated as an adjustable device to generate various combinations of short-lived reactive oxygen and nitrogen species (RONS) and as a promising appliance for cancer therapy. This study investigated the effects of direct and indirect treatments of Argon-based CAP to cancer cells (A2058, A549, U2OS and BCC) and fibroblasts (NIH3T3 and L929) on cell viability. We also aimed to understand whether plasma-generated RONS were involved in this process using genetic evidence.
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