AI Article Synopsis
- The study investigates the connections between obesity, Vitamin D deficiency, and protein oxidation in children, comparing various metabolic markers across different weight categories.
- Results show that obese children had significantly lower Vitamin D levels compared to their pre-obese and normal-weight peers, with additional findings indicating that these levels vary by gender and developmental stage.
- High triglyceride levels were linked to disruptions in thiol-disulfide balance, highlighting that low Vitamin D, puberty, and elevated triglycerides negatively impact this system.
Article Abstract
The aim of the study is to examine the relationship between obesity, Vitamin-D deficiency, and protein oxidation. Thiol-disulfide homeostasis, Vitamin-D, ischemia modified albumin, insulin, and lipid levels were compared among obese, pre-obese and normal-weight healthy children. A total of 136 children (69 boys and 67 girls) were included in the study. The vitamin-D levels of obese children were lower than those of pre-obese and normal weight (p < 0.05). In the normal weight group, total thiol and native thiol were lower in the pubertal period than in adolescence; were higher in those with sufficient Vitamin-D level than those with insufficient and deficient Vitamin-D (p < 0.05). Vitamin-D level was lower in pre-obese girls than boys (p < 0.05). Those with high triglycerides had high disulfide/total thiol, disulfide, and disulfide/native thiol and low native thiol/total thiol (p < 0.05). Thiol-disulfide homeostasis is negatively affected by low vitamin D levels, pubertal period and high triglyceride levels.
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| http://dx.doi.org/10.1080/15513815.2023.2183026 | DOI Listing |
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