Summary: Transcription factors (TFs) are proteins that directly interpret the genome to regulate gene expression and determine cellular phenotypes. TF identification is a common first step in unraveling gene regulatory networks. We present CREPE, an R Shiny app to catalogue and annotate TFs. CREPE was benchmarked against curated human TF datasets. Next, we use CREPE to explore the TF repertoires of and butterflies.
Availability And Implementation: CREPE is available as a Shiny app package available at GitHub (github.com/dirostri/CREPE).
Supplementary Information: Supplementary data are available at online.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162806 | PMC |
| http://dx.doi.org/10.1093/bioadv/vbad055 | DOI Listing |
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CREPE: a Shiny app for transcription factor cataloguing.
Bioinform Adv
April 2023
Department of Biology, University of Puerto Rico Río Piedras, San Juan 00925, Puerto Rico.
Summary: Transcription factors (TFs) are proteins that directly interpret the genome to regulate gene expression and determine cellular phenotypes. TF identification is a common first step in unraveling gene regulatory networks. We present CREPE, an R Shiny app to catalogue and annotate TFs.
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