The title compound, CHO, is a steroid synthesized through a rearrangement of a sarsasapogenin derivative in acidic medium. The newly formed ring is a tetra-hydro-2-pyran heterocycle substituted by two methyl groups placed in equatorial positions. This ring displays a chair conformation, while di-hydro-furan ring , to which it is bonded, has an envelope conformation. The mol-ecules are associated by weak O-H⋯O hydrogen bonds to form chains running in the [101] direction in the crystal.
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http://dx.doi.org/10.1107/S2414314623003449 | DOI Listing |
BMJ Open
December 2024
Cardiology, VieCuri Medical Centre, Venlo, Limburg, Netherlands.
Introduction: Ischaemic heart disease is the single most common cause of death worldwide. Traditionally, distinguishing patients with cardiac ischaemia from patients with less alarming disease, in prehospital triage of chest pain, is challenging for both general practitioners and ambulance paramedics. Less than 20% of patients with chest pain, transferred to the emergency department (ED), have an acute coronary syndrome (ACS) and the transportation and analysis at the ED of non-ACS patients result in substantial healthcare costs and a great patient burden.
View Article and Find Full Text PDFDalton Trans
January 2025
State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210023, China.
Silicon-based anode materials experience significant volume changes and low conductivity during the lithiation process, which severely hinders their successful application in lithium-ion batteries. Reducing the size of silicon particles and effectively combining them with carbon-based materials are considered the main strategies to enhance the lithium-ion storage performance of silicon-based anodes. In this study, we employed a "bottom-up" strategy to synthesize Si@C anode materials by cross-linking octa-aminopropyl polyhedral oligomeric silsesquioxane (NH-POSS) with terephthalaldehyde and subsequent high-temperature treatment and low-temperature liquid reduction.
View Article and Find Full Text PDFJMIR Med Inform
January 2025
Center for Medical Sciences, Ibaraki Prefectural University of Health Sciences, Ami-machi, Japan.
Background: Residents of facilities for older people are vulnerable to COVID-19 outbreaks. Nevertheless, timely recognition of outbreaks at facilities for older people at public health centers has been impossible in Japan since May 8, 2023, when the Japanese government discontinued aggressive countermeasures against COVID-19 because of the waning severity of the dominant Omicron strain. The Facility for Elderly Surveillance System (FESSy) has been developed to improve information collection.
View Article and Find Full Text PDFIndian J Crit Care Med
January 2025
Department of Medicine and Nephrology, Command Hospital (SC), Pune, Maharashtra, India.
Ghosh I, Sangha SS, Pandey G, Srivastava A. Author Response: Insights into Immunomodulatory Therapy for Sepsis. Indian J Crit Care Med 2025;29(1):91.
View Article and Find Full Text PDFCogn Neurodyn
December 2025
Shanghai University, Shanghai, China.
Neurodynamic observations indicate that the cerebral cortex evolved by self-organizing into functional networks, These networks, or distributed clusters of regions, display various degrees of attention maps based on input. Traditionally, the study of network self-organization relies predominantly on static data, overlooking temporal information in dynamic neuromorphic data. This paper proposes Temporal Self-Organizing (TSO) method for neuromorphic data processing using a spiking neural network.
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