Like in many other African countries, pig production is increasing in Tanzania. To support farmers and stakeholders, it is important to increase our understanding of porcine pathogens present in the country. Currently, little is known about the circulation of porcine circovirus-2 (PCV-2) and porcine circovirus-3 (PCV-3). For this reason, samples from 124 pigs collected throughout the country between 2018 to 2022 were screened by PCR for the presence of PCV-2 and PCV-3. Sequencing and phylogenetic analysis of positive amplicons identified two PCV-2 genotypes (a and d). Limited genetic heterogenicity was observed among the PCV-3. This study provides important data on pathogens present in pigs in Tanzania and should be of use veterinary authorities involved in porcine disease management.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315549 | PMC |
| http://dx.doi.org/10.1292/jvms.23-0031 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Using diagnostic data from veterinary diagnostic laboratories to unravel macroepidemiological aspects of porcine circoviruses 2 and 3 in the United States from 2002-2023.
PLoS One
December 2024
Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, United States of America.
Porcine circoviruses (PCVs), including porcine circovirus 2 (PCV2) and porcine circovirus 3 (PCV3), have been associated with clinical syndromes in swine, resulting in significant economic losses. To better understand the epidemiology and clinical relevance of PCV2 and PCV3, this study analyzed a dataset comprising diagnostic data from six veterinary diagnostic laboratories (VDLs) in the United States of America. The data comprised of polymerase chain reaction (PCR) test results, sample type, and age group for PCV2 and PCV3 submissions from 2002-2023.
View Article and Find Full Text PDFNewcastle Disease Virus Expressing Cap Gene of Porcine Circovirus Type 2 Confers Protection in Mice and Induced Long-Lasting Neutralizing Antibodies in Pigs.
Vaccines (Basel)
November 2024
Recombinant DNA Laboratory, Division of Veterinary Biotechnology, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly 243122, UP, India.
: Porcine Circovirus 2 (PCV2) infection poses significant health and economic challenges to the global swine industry. The disease in pigs leads to lymphoid depletion, resulting in immunosuppression and increased susceptibility to co-infections with other bacterial and viral pathogens. This study evaluated the efficacy of two novel recombinant Newcastle disease virus (NDV) strain R2B vectored vaccines that express the cap gene of PCV2 alone and along with the transmembrane and cytoplasmic tail (TMCT) domains of the NDV F gene.
View Article and Find Full Text PDFA case report of porcine circovirus 3 (PCV3) reproductive disease in Iberian semi-outdoor reared sows.
Porcine Health Manag
November 2024
Unitat mixta d'investigació IRTA- UAB en Sanitat Animal, Centre de Recerca en Sanitat Animal (CReSA), Campus de la Universitat Autònoma de Barcelona (UAB), Bellaterra, Catalonia, 08193, Spain.
Article Synopsis
- Porcine circovirus 3 (PCV3) is a newly identified pathogen linked to reproductive issues in pigs, notably in intensive farming setups.
- A case study from a semi-outdoor Iberian sow farm highlighted significant reproductive disease symptoms, including a rise in mummified fetuses and stillborn piglets primarily among gilts, while multiparous sows remained unaffected.
- Investigations confirmed the presence of PCV3 through tissue analysis, displaying specific lesions such as lymphohistiocytic myocarditis, marking the first documented incidence of PCV3 reproductive disease in this farming system.
An updated phylogeography and population dynamics of porcine circovirus 2 genotypes: are they reaching an equilibrium?
Front Microbiol
October 2024
Departament de Sanitat i Anatomia Animals, Facultat de Veterinària, UAB, Barcelona, Spain.
Introduction: Porcine circovirus 2 (PCV2) emerged more than three decades ago as one of the most impactful pathogens in the swine industry. Despite being a DNA virus, one of the hallmarks of PCV2 is its high evolutionary rate, which has led to the emergence of different genotypes, each exhibiting varying degrees of evolutionary success. Current knowledge suggests the occurrence of three main waves of genotype dominance, alternating over time (i.
View Article and Find Full Text PDFRetrospective investigation of porcine circoviruses in cases of porcine dermatitis and nephropathy syndrome.
Vet Res
November 2024
Unitat Mixta d'Investigació IRTA-UAB en Sanitat Animal, Centre de Recerca en Sanitat Animal (CReSA), Campus de la Universitat Autònoma de Barcelona (UAB), 08193, Bellaterra, Barcelona, Spain.
Article Synopsis
- - Porcine dermatitis and nephropathy syndrome (PDNS) is a serious condition affecting pigs, mainly linked to porcine circovirus 2 (PCV-2) and potentially associated with other strains (PCV-3 and PCV-4).
- - A study analyzed 102 PDNS cases through various methods like PCR and immunohistochemistry to investigate the presence of different porcine circoviruses.
- - Results showed that all PDNS cases tested positive for PCV-2, with a subset also showing PCV-3, while no link was found between PDNS and PCV-1 or PCV-4, reinforcing the idea that PCV-2 is likely the primary cause of PDNS
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!