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http://dx.doi.org/10.1016/j.radonc.2023.109691 | DOI Listing |
BMC Palliat Care
January 2025
School of Medicine, University of Dundee, Dundee, UK.
Background: Discussing Advance Care Planning (ACP) with people living with dementia (PwD) is challenging due to topic sensitivity, fluctuating mental capacity and symptom of forgetfulness. Given communication difficulties, the preferences and expectations expressed in any ACP may reflect family and healthcare professional perspectives rather than the PwD. Starting discussions early in the disease trajectory may avoid this, but many PwD may not be ready at this point for such discussions.
View Article and Find Full Text PDFBMC Med Educ
January 2025
Dubai Medical College, Dubai, United Arab Emirates.
Within the context of competency-based medical education, portfolios and mentorship emerge as complementary interventions, each offering distinct perspectives and benefits. Together, these elements synergistically contribute to a holistic and effective approach to medical education, encompassing both the academic and personal development imperatives of students. However, this integration comes with several implementation challenges that must be anticipated and promptly addressed.
View Article and Find Full Text PDFBMC Med Genomics
January 2025
Administrative Office, The Fourth People's Hospital of Nanning, Nanning, China.
Background: Chronic obstructive pulmonary disease (COPD) is a chronic and progressive lung disease. Disulfidptosis-related genes (DRGs) may be involved in the pathogenesis of COPD. From the perspective of predictive, preventive, and personalized medicine (PPPM), clarifying the role of disulfidptosis in the development of COPD could provide a opportunity for primary prediction, targeted prevention, and personalized treatment of the disease.
View Article and Find Full Text PDFBMC Nurs
January 2025
The First Affiliated Hospital of China Medical University, No.155, Nanjing North Street, Heping District, Shenyang, Liaoning Province, China.
Background: Self-management is regarded as a crucial factor influencing the effectiveness of home-based cardiac rehabilitation for patients with coronary heart disease. In nursing practice, nurses employ a variety of strategies to enhance self-management of patients. However, there exists a disparity in nurses' perceptions and practical experiences with these strategies.
View Article and Find Full Text PDFNature
January 2025
Murdoch Children's Research Institute, Melbourne, Victoria, Australia.
Polygenic genome editing in human embryos and germ cells is predicted to become feasible in the next three decades. Several recent books and academic papers have outlined the ethical concerns raised by germline genome editing and the opportunities that it may present. To date, no attempts have been made to predict the consequences of altering specific variants associated with polygenic diseases.
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