Estimates of ocean [Formula: see text] uptake from global ocean biogeochemistry models and [Formula: see text]-based data products differ substantially, especially in high latitudes and in the trend of the [Formula: see text] uptake since 2000. Here, we assess the effect of data sparsity on two [Formula: see text]-based estimates by subsampling output from a global ocean biogeochemistry model. The estimates of the ocean [Formula: see text] uptake are improved from a sampling scheme that mimics present-day sampling to an ideal sampling scheme with 1000 evenly distributed sites. In particular, insufficient sampling has given rise to strong biases in the trend of the ocean carbon sink in the [Formula: see text] products. The overestimation of the [Formula: see text] flux trend by 20-35% globally and 50-130% in the Southern Ocean with the present-day sampling is reduced to less than [Formula: see text] with the ideal sampling scheme. A substantial overestimation of the decadal variability of the Southern Ocean carbon sink occurs in one product and appears related to a skewed data distribution in [Formula: see text] space. With the ideal sampling, the bias in the mean [Formula: see text] flux is reduced from 9-12% to 2-9% globally and from 14-26% to 5-17% in the Southern Ocean. On top of that, discrepancies of about [Formula: see text] (15%) persist due to uncertainties in the gas-exchange calculation. This article is part of a discussion meeting issue 'Heat and carbon uptake in the Southern Ocean: the state of the art and future priorities'.
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http://dx.doi.org/10.1098/rsta.2022.0063 | DOI Listing |
BMC Pediatr
December 2024
Vanderbilt University School of Medicine, Nashville, TN, USA.
Background: Recurrent tonsillitis is a common indication for tonsillectomy in children and has phenotypic overlap with periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome. We sought to characterize symptoms associated with PFAPA among children undergoing tonsillectomy.
Methods: Parents/guardians of children undergoing tonsillectomy at Vanderbilt Children's Hospital over a six-week period were queried regarding symptoms of recurrent fever.
Am J Chin Med
December 2024
Acupuncture and Rehabilitation Centre, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510000, Guangdong, P. R. China.
Parkinson's disease (PD) is a progressive neurodegenerative disorder without a definitive cure. Oriental exercises (OEs) have emerged as a complementary and alternative therapy for PD, but their efficacy in ameliorating non-motor symptoms (NMS) and quality of life (QOL) remains uncertain. This systematic review and meta-analysis actively investigated the efficacy of OEs in addressing NMS and enhancing QOL and sought to offer recommendations for optimal OE regimens for PD patients.
View Article and Find Full Text PDFAm J Chin Med
December 2024
The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510000, P. R. China.
Ginseng-containing Shentao Ruangan granules (STR) have been a well-known Chinese medicine prescription for the treatment of hepatocellular carcinoma (HCC) in China for decades. This study aimed to establish an experimental framework to decipher the underlying mechanism of STR in the treatment of HCC. Microarray analysis, network pharmacology, RNA-sequencing (RNA-seq), bioinformatics analysis, and and experiments were used as integrated approaches to uncover the effects and mechanisms of action of STR.
View Article and Find Full Text PDFAm J Chin Med
December 2024
Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang 150040, P. R. China.
Alzheimer's disease (AD), the predominant form of dementia, is a neurodegenerative disorder of the central nervous system (CNS) characterized by a subtle onset and a spectrum of cognitive and functional declines. The clinical manifestation of AD encompasses memory deficits, cognitive deterioration, and behavioral disturbances, culminating in a severe impairment of daily living skills. Despite its high prevalence, accounting for 60-70% of all dementia cases, there remains an absence of curative therapeutics.
View Article and Find Full Text PDFSci Total Environ
December 2024
Faculty of Mathematics and Physics, Charles University, Sokolovska 49, 186 75 Prague, Czech Republic.
In many countries worldwide, NO emissions currently decrease as a result of pollution control, while NH emissions stagnate or continue to increase. Little is known about horizontal deposition of NO and NH, the oxidation/neutralization products of these primary pollutants. To close the knowledge gap, we studied atmospheric inputs of NO and NH at two mountain-top sites near the Czech-German-Polish borders during winter.
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