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Combined liver-kidney transplantation with delayed kidney implantation: A case report. | LitMetric

Combined liver-kidney transplantation with delayed kidney implantation: A case report.

Int J Surg Case Rep

Department of Surgery, Division of HPB & Transplant Surgery, Erasmus MC University Transplant Institute, Rotterdam, the Netherlands. Electronic address:

Published: May 2023

AI Article Synopsis

Article Abstract

Introduction: In rare cases, patients require a combined liver-kidney transplant. However, the peri- and postoperative care of liver transplant recipients differs from kidney transplant recipients, which can lead to conflicts of interest. In the case of poor coagulation status and/or instable hemodynamics of the patient, liver transplantation, followed by delayed kidney transplantation can lead to better postoperative recovery.

Presentation Of Case: In our case report, we present a 48-year old man with Alagille syndrome and IgA nephropathy with bilirubin-associated acute kidney injury, causing him to develop both end-stage liver and kidney disease. He underwent a combined liver-kidney transplant as the first patient in the Netherlands, in which the donor kidney was transplanted one day after the liver transplantation. One-year post-transplant patient is in good clinical condition, with normal liver function and an eGFR of 57 ml/min.

Conclusion: Combined liver-kidney transplantation with delayed kidney implantation in a medical center with no previous experience with this technique is feasible and safe. This could be better for both the patient and the kidney graft.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10195974PMC
http://dx.doi.org/10.1016/j.ijscr.2023.108276DOI Listing

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