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| http://dx.doi.org/10.1186/s13000-023-01345-5 | DOI Listing |
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Boosting skin cancer diagnosis accuracy with ensemble approach.
Sci Rep
January 2025
School of Information and Electronic Engineering and Zhejiang Key Laboratory of Biomedical Intelligent Computing Technology, Zhejiang University of Science and Technology, No. 318, Hangzhou, Zhejiang, China.
Skin cancer is common and deadly, hence a correct diagnosis at an early age is essential. Effective therapy depends on precise classification of the several skin cancer forms, each with special traits. Because dermoscopy and other sophisticated imaging methods produce detailed lesion images, early detection has been enhanced.
View Article and Find Full Text PDFThe first use of "lupus" as a disease.
Lupus
January 2025
Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.
Objectives: Describe the history of the use of the term "lupus" as a disease and to point out the inaccuracies of previous lupus historical articles and correct the historical record.
Methods: An exhaustive review of Medieval and later texts regarding the use of the term "lupus" as it was used for the name of a disease as well as personal communications with Medieval experts who have studied this topic.
Results: There are three possible first uses of "lupus" as a disease: an affidavit written in 963 AD by Eraclius (Bishop of Liège, Belgium), in a 12th century historical account of the Bishop of Liège, falsely ascribed to the 9th century Bishop Herbernus, or in an 1170 AD letter written by Pierre de Blois about the death of archbishop Stephan du Perche.
Revisiting the functional annotation of TriTryp using sequence similarity tools.
Heliyon
October 2024
Institute of Parasitology, McGill University, Canada.
Trypanosomatids are the causative agents of deadly diseases in humans and livestock. Given the high phylogenetic distance of trypanosomatids from model organisms, these organisms have ample unannotated genes. Manual functional annotation is time-consuming, highlighting the importance of automated functional annotation tools.
View Article and Find Full Text PDFA novel quinazoline derivative exhibits potent anticancer cytotoxicity via apoptosis and inhibition of angiogenesis in DMBA-induced mammary gland carcinoma.
J Biochem Mol Toxicol
November 2024
Department of Pharmaceutical Sciences, Babasaheb Bhimrao Ambedkar University (A Central University), Lucknow, India.
Mammary gland carcinoma is one of the most prevalent and deadly diseases among women globally. It is a type of solid malignant tumor. In this malignant tumor, the microenvironment becomes hypoxic in rapidly proliferating cancer cells.
View Article and Find Full Text PDFThe Best ECG Lead for Predicting the Risk of Drug-Induced Torsade De Pointes Using Corrected QT Interval: A Comparative Prognostic Study.
Arch Acad Emerg Med
September 2024
Department of Emergency Medicine, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Dusit, Bangkok, Thailand, 10300.
Introduction: Torsade de pointes (TdP) is a deadly complication from drug-induced QT prolongation. Each of the 12 lead of an electrocardiogram (ECG) has a different length of QT interval, and thus might have a different performance in TdP prediction. This study aimed to determine the best ECG lead or set of leads in this regard.
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