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Severe acute drug-induced dystonia in the post-operative period requiring tracheal re-intubation.
Anaesth Rep
November 2023
Department of Anaesthesia North Bristol Trust Bristol UK.
Ondansetron is a highly selective 5-hydroxytryptamine receptor antagonist and the most commonly used anti-emetic for the prevention of postoperative nausea and vomiting. Ondansetron has a low affinity for dopamine receptors and so extrapyramidal side effects are rare. Here, we present the case of a 14-year-old girl who developed a severe post-operative acute dystonic reaction which included oculogyric crisis.
View Article and Find Full Text PDFOndansetron-induced oculogyric crisis in a pediatric patient: case report.
CJEM
June 2023
Department of Emergency Medicine, University of Health Sciences Kocaeli Derince Training and Research Hospital, Kocaeli, Turkey.
Ondansetron-induced oculogyric crisis.
Eur J Anaesthesiol
December 2014
From the Department of Anaesthesia, Khoo Teck Puat Hospital, Yishun, Singapore.
Ondansetron-induced multifocal encephalopathy.
Mayo Clin Proc
September 2003
Department of Anesthesiology, Mayo Clinic, Rochester, Minn. 55905, USA.
We treated a patient who developed transient multifocal encephalopathy with extrapyramidal symptoms (oromandibular dystonia, oculogyric crisis, and limb dystonia) in temporal proximity to ondansetron administration on emergence from general anesthesia. No other medications known to cause extrapyramidal reactions were administered. Although these symptoms resolved fully, the presentation was dramatic and resembled the symptoms of structural brain injury.
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