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Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of an essential oil from the leaves of L. (sage oil) when used as a sensory additive in feed and in water for drinking for all animal species. The EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) concluded that sage oil is considered safe up to the maximum proposed use levels in complete feed of 20 mg/kg for ornamental fish.
View Article and Find Full Text PDFMayfly developmental atlas: developmental temporal expression atlas of the mayfly, Ephemera vulgata, reveals short germ-specific hox gene activation.
BMC Genomics
December 2024
Biosystematics group, Wageningen University & Research, Droevendaalsesteeg 1, Wageningen, The Netherlands, 6708PB.
Article Synopsis
- The study focuses on the early developmental stages of the mayfly Ephemera vulgata, an ancient flying insect, to better understand ancestral modes of insect development which have been under-researched compared to more modern insects.
- Through DAPI staining and extensive RNA sequencing, researchers created a detailed expression atlas and identified over 6,000 differentially expressed genes across various developmental timepoints.
- The findings highlight a structured progression in embryonic development, revealing important correlations between genetic expression and the formation of major anatomical structures, as well as insights into the ancestral short germ segmentation process.
Effect of Dietary Concentrate-to-Forage Ratios During the Cold Season on Slaughter Performance, Meat Quality, Rumen Fermentation and Gut Microbiota of Tibetan Sheep.
Animals (Basel)
November 2024
College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
This study aimed to investigate the effects of different dietary concentrate-to-forage ratios on slaughter performance, meat quality, rumen fermentation, rumen microbiota and fecal microbiota in Tibetan sheep. A total of sixty male Tibetan sheep were equally allocated into three dietary groups based on concentrate-to-forage ratios, i.e.
View Article and Find Full Text PDFDevelopment of a novel glucose-dendrimer based therapeutic targeting hyperexcitable neurons in neurological disorders.
Bioeng Transl Med
September 2024
Article Synopsis
- * A new glucose-dendrimer (GD2) was developed to selectively target hyperexcitable neurons, which showed promising results in various models, including lab cultures and live mice.
- * By linking GD2 with the anti-epileptic drug valproic acid (GD2-VPA) and delivering it intranasally, researchers achieved a significant reduction in seizure severity, indicating potential for targeted neuroprotection and improved neuronal health.
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of an essential oil from the fresh or dried flowering stems of L. (clary sage oil) when used as a sensory additive in feed and in water for drinking for all animal species. The EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) concluded that the additive under assessment is considered safe up to the maximum use level in complete feed of 15 mg/kg for veal calves (milk replacers), cattle for fattening, sheep/goats, 10 mg/kg for horses, 20 mg/kg for dogs, salmonids and ornamental fish.
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