Facilitated osteogenesis of magnesium implant by coating of strontium incorporated calcium phosphate.

Biointerphases

Department of Dental Biomaterials and Institute of Biodegradable material, Institute of Oral Bioscience, School of Dentistry, Jeonbuk National University, Jeonju 54896, South Korea.

Published: May 2023

This study investigated the corrosion resistance and biocompatibility of magnesium coated with strontium-doped calcium phosphate (Sr-CaP) for dental and orthopedic applications. Sr-CaP was coated on biodegradable magnesium using a chemical dipping method. Magnesium coated with Sr-CaP exhibited better corrosion resistance than pure magnesium. Sr-CaP-coated magnesium showed excellent cell proliferation and differentiation. Additionally, new bone formation was confirmed in vivo. Therefore, Sr-CaP-coated magnesium with reduced degradation and improved biocompatibility can be used for orthopedic and dental implant applications.

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Source
http://dx.doi.org/10.1116/6.0002598DOI Listing

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