Unlabelled: Clown nose-like lesion can be the manifestation of inflammatory, infectious or neoplasm-related diseases, and some genetic syndromes. Lung carcinoma metastasize rarely to the skin. To our knowledge, 16 cases of lung cancer metastasis with clown nose-like lesions have been reported. Here, we describe a new case.

Abstract: Cutaneous metastases of small-cell-lung carcinoma are rare, and nose involvement is much rarer. However, it can be the first warning sign of lung cancer. We describe the case of a patient who presented with a red nodule of the nasal tip reminding a clown-nose.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151591PMC
http://dx.doi.org/10.1002/ccr3.7249DOI Listing

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Article Synopsis
  • Clowns are not only popular in entertainment but also have inspired names in dermatology, referred to as medical eponyms.
  • The text identifies four clown-related eponyms: clown nose-like lesion, clown eczema, clown alopecia pattern in frontal fibrosing alopecia, and clown's face in Brachman de Lange syndrome.
  • It also recognizes the significant role of medical clowning in healthcare, specifically honoring Cobo the Clown, a dedicated clown who has contributed to patient care for over thirty years.
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Unlabelled: Clown nose-like lesion can be the manifestation of inflammatory, infectious or neoplasm-related diseases, and some genetic syndromes. Lung carcinoma metastasize rarely to the skin. To our knowledge, 16 cases of lung cancer metastasis with clown nose-like lesions have been reported.

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Clown nose-like lesion refers to the manifestation of a reddish or skin-colored bulge on the tip of the nose or the manifestation of bulbous tip of the nose. More and more clinical cases show that clown nose-like lesion can also be the indication of some genetic syndromes, not just the manifestation of metastatic visceral tumor as it initially proposed. However, the clinical features of clown nose-like lesion indicated by metastatic malignancies, genetic cancer predisposition syndromes or primary diseases involving the nasal tip are lacking.

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