AI Article Synopsis

  • The decline in fertility rates and the trend of women having children at older ages are major reasons for low pregnancy success rates in developed countries.
  • Epigenetic factors, which affect gene expression and can influence embryonic development, play a significant role in the outcomes of women undergoing IVF treatment.
  • The text outlines key epigenetic modifications that could impact female reproductive health and potentially improve the success rates of IVF.

Article Abstract

The constant decline in fertility and older reproductive age is the major cause of low clinical pregnancy rates in industrialised countries. Epigenetic mechanisms impact on proper embryonic development in women undergoing in vitro fertilisation (IVF) protocols. Here, we describe the main epigenetic modifications that may influence female reproduction and could affect IVF success.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161563PMC
http://dx.doi.org/10.1186/s13148-023-01490-0DOI Listing

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