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Study Design: This is a report of methods and tools for selection of task and individual configurations targeted for voluntary movement, standing, stepping, blood pressure stabilization, and facilitation of bladder storage and emptying using tonic-interleaved excitation of the lumbosacral spinal cord.
Objectives: This study aimed to present strategies used for selection of stimulation parameters for various motor and autonomic functions.
Conclusions: Tonic-interleaved functionally focused neuromodulation targets a myriad of consequences from spinal cord injury with surgical implantation of the epidural electrode at a single location. This approach indicates the sophistication of the human spinal cord circuitry and its important role in the regulation of motor and autonomic functions in humans.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624649 | PMC |
| http://dx.doi.org/10.1016/j.neurom.2023.03.014 | DOI Listing |
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