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Clinical characterization of a novel p.Gly615Glu mutation in nine family members with familial hemiplegic migraine.
Brain Commun
December 2024
Dipartimento Universitario di Neuroscienze, Università Cattolica del Sacro Cuore, 00168 Roma, Italy.
Familial hemiplegic migraine type 2 results from pathogenic variants in the gene, which encodes for a catalytic subunit of sodium/potassium ATPase. This extremely rare autosomal dominant disorder manifests with a spectrum of symptoms, most commonly pure hemiplegic phenotype, epilepsy, and/or intellectual disability. In this study, we detail the clinical features and genetic analysis of nine patients from a large family spanning four generations, with all carrying a previously unreported likely pathogenic variant, p.
View Article and Find Full Text PDFEpidemiological, clinical characterization and treatment patterns of migraine patients in a Colombian cohort from 2018 to 2022.
J Headache Pain
December 2024
Pfizer SAS, Bogota, Colombia.
Background: To describe the epidemiology and clinical characteristics of migraine and the status of treatment in Colombia. Additionally, the use of health resources by patients was measured.
Methods: This was a non-interventional, retrospective, descriptive study conducted in one Colombian Health Management Organization (HMO) from 2018 to 2022 with a follow-up period of 5 years.
Evaluation of the Frequency of Migraine and CVA Patients Based on Circle of Willis Morphological Variations in MRA Images.
Adv Biomed Res
November 2024
Medical Faculty, Abadan University of Medical Sciences, Abadan, Iran.
Background: The Circle of Willis (CoW) forms a critical collateral route for the compensation pathway at the basal cistern of the brain. This study aims to determine if migraine headaches and cerebrovascular accidents (CVAs) are associated with the prevalence and patterns of CoW arterial variations seen in the three-dimensional time-of-flight magnetic resonance angiography technique in patients.
Materials And Methods: A cross-sectional study was undertaken by a systemic search of electronic databases in the Imaging Center, Abadan's Taleghani Hospital, Iran, from March 2020 to March 2022.
Correlation between endometriosis and migraine headache - a review of literature.
Wiad Lek
December 2024
GRADUATE OF THE FACULTY OF MEDICINE, POZNAN UNIVERSITY OF MEDICAL SCIENCES, POZNAN, POLAND; UNIVERSITY CLINICAL HOSPITAL IN POZNAN, POZNAN. POLAND.
Objective: Aim: Endometriosis and migraine are common diseases that share many features, and their co-occurrence is the subject of numerous studies. Nevertheless, there is no effective treatment for these diseases and diagnosis is often delayed. This review aims to present correlations between these conditions, which can improve diagnosis and treatment.
View Article and Find Full Text PDFGestational Hypertension, Preeclampsia, and Eclampsia and Future Neurological Disorders.
JAMA Neurol
December 2024
Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
Importance: Gestational hypertension, preeclampsia, and eclampsia are established risk factors for stroke and dementia later in life. Whether these pregnancy complications are associated with an increased risk of new-onset neurological disorders within months to years after giving birth is not known.
Objective: To explore whether gestational hypertension, preeclampsia, and eclampsia are associated with new-onset migraine, headache, epilepsy, sleep disorder, or mental fatigue within months to years after giving birth.
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