AI Article Synopsis
- The study investigates the link between appendicular skeletal muscle mass (ASM) and cardiometabolic risk, focusing on Korean adolescents' percentage of ASM (PASM) and its relationship with metabolic syndrome (MS).
- Data from the Korea National Health and Nutrition Examination Survey revealed that PASM changes with age differ between boys, who see an increase, and girls, who experience a decline. Higher PASM values were linked to lower risks of obesity, abdominal obesity, hypertension, and elevated triglycerides.
- The findings suggest that maintaining higher ASM can reduce the risk of developing MS and insulin resistance, emphasizing the importance of monitoring body composition in clinical settings for better patient management.
Article Abstract
Purpose: The association between appendicular skeletal muscle mass (ASM) and cardiometabolic risk has been emphasized. We estimated reference values of the percentage of ASM (PASM) and investigated their association with metabolic syndrome (MS) in Korean adolescents.
Methods: Data from the Korea National Health and Nutrition Examination Survey performed between 2009 and 2011 were used. Tables and graphs of reference PASM were generated using 1,522 subjects, 807 of whom were boys aged 10 to 18. The relationship between PASM and each component of MS in adolescents was further analyzed in 1,174 subjects, 613 of whom were boys. Moreover, the pediatric simple MS score (PsiMS), the homeostasis model assessment of insulin resistance (HOMA-IR), and the triglyceride-glucose (TyG) index were analyzed. Multivariate linear and logistic regressions adjusting for age, sex, household income, and daily energy intake were performed.
Results: In boys, PASM increased with age; the trend was different in girls, in whom PASM declined with age. PsiMS, HOMA-IR, and TyG index showed inverse associations with PASM (PsiMS, β=-0.105, P<0.001; HOMA-IR, β=-0.104, P<0.001; and TyG index, β=-0.013, P<0.001). PASM z-score was negatively associated with obesity (adjusted odds ratio [aOR], 0.22; 95% CI, 0.17-0.30), abdominal obesity (aOR, 0.27; 95% CI, 0.20-0.36), hypertension (aOR, 0.65; 95% CI, 0.52-0.80), and elevated triglycerides (aOR, 0.67; 95% CI, 0.56-0.79).
Conclusion: The probability of acquiring MS and insulin resistance decreased as PASM values increased. The reference range may offer clinicians information to aid in the effective management of patients. We urge clinicians to monitor body composition using standard reference databases.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10765024 | PMC |
| http://dx.doi.org/10.6065/apem.2244268.134 | DOI Listing |
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