Energy saver: Monocytes hibernate in bone marrow upon fasting.

Cell Metab

Department of Pediatrics and Adolescent Medicine, Ulm University Medical Center, Ulm, Germany. Electronic address:

Published: May 2023

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Article Abstract

Immune functions are influenced by the nutritional state. In a recent publication in Immunity, Janssen et al. unveil that a fasting-induced glucocorticoid release makes monocytes move from blood into the bone marrow. Upon refeeding, these chronologically older monocytes are again released and exert detrimental effects during bacterial infection.

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Source
http://dx.doi.org/10.1016/j.cmet.2023.04.008DOI Listing

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