Weakly supervised temporal action localization (WTAL) aims to classify and localize temporal boundaries of actions for the video, given only video-level category labels in the training datasets. Due to the lack of boundary information during training, existing approaches formulate WTAL as a classification problem, i.e., generating the temporal class activation map (T-CAM) for localization. However, with only classification loss, the model would be suboptimized, i.e., the action-related scenes are enough to distinguish different class labels. Regarding other actions in the action-related scene (i.e., the scene same as positive actions) as co-scene actions, this suboptimized model would misclassify the co-scene actions as positive actions. To address this misclassification, we propose a simple yet efficient method, named bidirectional semantic consistency constraint (Bi-SCC), to discriminate the positive actions from co-scene actions. The proposed Bi-SCC first adopts a temporal context augmentation to generate an augmented video that breaks the correlation between positive actions and their co-scene actions in the inter-video. Then, a semantic consistency constraint (SCC) is used to enforce the predictions of the original video and augmented video to be consistent, hence suppressing the co-scene actions. However, we find that this augmented video would destroy the original temporal context. Simply applying the consistency constraint would affect the completeness of localized positive actions. Hence, we boost the SCC in a bidirectional way to suppress co-scene actions while ensuring the integrity of positive actions, by cross-supervising the original and augmented videos. Finally, our proposed Bi-SCC can be applied to current WTAL approaches and improve their performance. Experimental results show that our approach outperforms the state-of-the-art methods on THUMOS14 and ActivityNet. The code is available at https://github.com/lgzlIlIlI/BiSCC.
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http://dx.doi.org/10.1109/TNNLS.2023.3266062 | DOI Listing |
J Integr Neurosci
January 2025
Department of Physical Therapy, Hangzhou Geriatric Hospital, 310022 Hangzhou, Zhejiang, China.
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View Article and Find Full Text PDFViruses
January 2025
Department of Veterinary Prevention and Avian Diseases, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, 20-033 Lublin, Poland.
Bacteriophages, as ubiquitous bacterial viruses in various natural ecosystems, play an important role in maintaining the homeostasis of the natural microbiota. For many years, bacteriophages were not believed to act on eukaryotic cells; however, recent studies have confirmed their ability to affect eukaryotic cells and interact with the host immune system. Due to their complex protein structure, phages can also directly or indirectly modulate immune processes, including innate immunity, by modulating phagocytosis and cytokine reactions, as well as acquired immunity, by producing antibodies and activating effector cells.
View Article and Find Full Text PDFPharmaceutics
January 2025
Department of Pharmacy, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen 518107, China.
: The mechanism of polysaccharide-based nanocarriers in enhancing photodynamic immunotherapy in colorectal cancer (CRC) remains poorly understood. : The effects of TPA-3BCP-loaded cholesteryl hemisuccinate- polysaccharide nanoparticles (DOP@3BCP NPs) and their potential molecular mechanism of action in a tumor-bearing mouse model of CRC were investigated using non-targeted metabolomics and transcriptomics. Meanwhile, a histopathological analysis (H&E staining, Ki67 staining, and TUNEL assay) and a qRT-PCR analysis revealed the antitumor effects of DOP@3BCP NPs with and without light activation.
View Article and Find Full Text PDFPharmaceutics
January 2025
Faculty of Pharmacy, University of Belgrade, 11221 Belgrade, Serbia.
This study aimed to develop gastroretentive tablets based on mucoadhesive-floating systems with encapsulated gentian (, Gentianaceae) root extract to overcome the low bioavailability and short elimination half-life of gentiopicroside, a dominant bioactive compound with systemic effect. The formulation also aimed to promote the local action of the extract in the stomach. Tablets were obtained by direct compression of sodium bicarbonate (7.
View Article and Find Full Text PDFJ Clin Med
January 2025
Management, Association for the Fight against Kidney Diseases ALCER, 28002 Madrid, Spain.
Chronic kidney disease-associated pruritus (CKD-aP) is underdiagnosed and not fully understood by healthcare professionals, which leads to poor patient management and impacts patients' quality of life (QoL). The aim of this study was to analyse unmet needs in CKD-aP management and explore the attributes/characteristics that the ideal CKD-aP treatment should have from the perspective of a group of nephrologists, hospital pharmacists, nurses, patient representatives, and regional health authorities in Spain. A descriptive, cross-sectional study was conducted using an e-survey including ad hoc questions (6-point Likert scale) related to unmet needs in CKD-aP and best-worst scaling (BWS) to prioritise the attributes/characteristics of the ideal CKD-aP treatment.
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