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Article Synopsis
  • Sickle cell cardiomyopathy is an often overlooked heart condition that significantly contributes to mortality among patients with sickle cell disease, particularly those with the HbSS genotype.
  • The study seeks to analyze the global longitudinal left ventricular strain in black patients with sickle cell disease in Nigeria and to find its relationship with various health measurements like ECG and clinical lab findings.
  • By examining 60 sickle cell patients alongside 60 healthy controls, researchers aim to track early heart changes across different ages, highlighting the importance of detecting cardiovascular issues in sickle cell disease beyond just lung-related complications.
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Background: Infected pancreatic necrosis (IPN) is a major determinant of mortality in acute pancreatitis (AP). Non-invasive diagnosis of IPN could guide the intervention in AP. We aimed to investigate the role of non-invasive methods like diffusion weighted magnetic resonance imaging (DW-MRI) and clinico-laboratory parameters as predictors of IPN.

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Thymoma with recurrent opportunistic infections-a case report.

Oxf Med Case Reports

September 2024

Department of Hematology, Apollo Hospitals, Chennai 600 006, Tamilnadu, India.

Article Synopsis
  • - Good's syndrome (GS) is a rare condition characterized by a thymoma that leads to both B-cell and T-cell immune deficiencies, resulting in increased vulnerability to infections.
  • - GS shares features with Common Variable Immunodeficiency (CVID), including low antibody levels (hypogammaglobulinemia) and higher risk for bacterial and opportunistic infections.
  • - A case study of a middle-aged woman with GS highlights the importance of recognizing thymoma as a potential precursor to immunodeficiency, and she showed improvement after receiving intravenous immunoglobulin treatment.
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Background: Up-to-date data about the role of acid suppression therapy e.g. proton-pump inhibitors; to reduce post-endoscopic variceal ligation (EVL) ulcer-bleeding are conflicting.

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Background: Anemia-causing fever has been described in patients with megaloblastic anemia. Although the exact mechanism of this is unknown, high-grade fever is relatively less reported.

Materials And Methods: This prospective observational study included all new cases of megaloblastic anemia presenting with febrile illness (>101°F) during a 3-year period.

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